Table 5 Multivariable-adjusted hazard ratios for ischemic vascular events according to migraine status in men and women according to data from the Women’s Health Study [88] and the Physician’s Health Study [89]
From: Comorbid neuropathologies in migraine: an update on cerebrovascular and cardiovascular aspects
Event | Women; HR (95% CI) | Men; HR (95% CI) | |||
|---|---|---|---|---|---|
No migraine (n = 22,715) | Migraine with aura (n = 1,434) | Migraine without aura (n = 2,176) | No migraine (n = 18,635) | Any migraine (n = 1,449) | |
Major cardiovascular event | 1 | 2.15 (1.58–2.92) P < 0.001 | 1.23 (0.88–1.73) P = 0.23 | 1 | 1.24 (1.06–1.46) P = 0.008 |
Ischemic stroke | 1 | 1.91 (1.17–3.10) P = 0.01 | 1.27 (0.77–2.09) P = 0.36 | 1 | 1.12 (0.84–1.50) P = 0.43 |
Myocardial infarction | 1 | 2.08 (1.30–3.31) P = 0.002 | 1.22 (0.73–2.05) P = 0.45 | 1 | 1.42 (1.15–1.77) P < 0.001 |
Coronary revascularization | 1 | 1.74 (1.23–2.46) P = 0.002 | 0.98 (0.67–1.42) P = 0.90 | 1 | 1.05 (0.89–1.24) P = 0.54 |
Angina | 1 | 1.71 (1.16–2.53) P = 0.007 | 1.12 (0.75–1.66) P = 0.58 | 1 | 1.15 (0.99–1.33) P = 0.07 |
Cardiovascular death | 1 | 2.33 (1.21–4.51) P = 0.01 | 1.06 (0.46–2.45) P = 0.89 | 1 | 1.07 (0.80–1.43) P = 0.65 |