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Table 1 Vmean of the middle cerebral artery (MCA) and diameters of the temporal (TA) and radial arteries (RA) during 5-ISMN and placebo [mean (absolute values), SEM]

From: Nitric oxide-induced headache may arise from extracerebral arteries as judged from tolerance to isosorbide-5-mononitrate

Time

Vmean, MCA (cm/s, SEM)

Diameter, TA (mm, SEM)

Diameter, RA (mm, SEM)

Hours

5-ISMN

Placebo

5-ISMN

Placebo

5-ISMN

Placebo

0

71 (4)

71 (4)

0.95 (0.04)

0.98 (0.04)

2.42 (0.09)

2.46 (0.09)

4

58 (3)

67 (4)

1.09 (0.04)

1.01 (0.04)

3.08 (0.17)

2.61 (0.13)

24

66 (4)

69 (4)

1.15 (0.03)

0.98 (0.03)

3.08 (0.12)

2.62 (0.11)

72

68 (3)

70 (3)

1.11 (0.05)

0.97 (0.03)

3.18 (0.15)

2.56 (0.09)

168

68 (3)

69 (3)

1.03 (0.04)

0.98 (0.04)

2.82 (0.13)

2.58 (0.11)

  1. MCA middle cerebral artery, TA temporal artery, RA radial artery, V mean mean blood velocity, SEM standard error of the mean