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Fig. 1 | The Journal of Headache and Pain

Fig. 1

From: Nitric oxide-induced headache may arise from extracerebral arteries as judged from tolerance to isosorbide-5-mononitrate

Fig. 1

The effect of 5-ISMN 30 mg t.i.d for 7 days on headache, mean blood flow velocity in middle cerebral artery and diameter of temporal artery. Headache was rated on a 0–10 scale. Median values are given. Percentage changes are given for the arteries. A close temporal association between the disappearance of headache and attenuation of the dilatory potency of 5-ISMN in the temporal artery was observed. The intracranial artery (middle cerebral artery) was already tolerant within 24 h

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The Journal of Headache and Pain

ISSN: 1129-2377

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