Skip to main content

Clinic–based study of family history of vascular risk factors and migraine

Abstract

The objective was to evaluate the presence of a positive family history (FH) of vascular risk factors between patients with migraine with aura (MA) and migraine without aura (MO), and in chronic migraine (CM) compared to other headache types. As migraine patients are typically too young to have developed vascular events, studying older relatives of migraine patients may be a practical means of evaluating associations between vascular risk factors and migraine. A cross–sectional study of a clinicbased sample of adults with migraine headache was carried out at the University of Utah. Predictor variables comprised first or second degree relatives with stroke, hypertension, diabetes or hypercholesterolaemia. Outcome measures comprised diagnosis of MA, MO or CM according to the revised International Headache Society criteria. There was no significant difference in FH of vascular risk factors in MA compared to MO (adjusted OR 1.04, 95% CI 0.61–1.78). CM was associated with a decreased risk of FH of stroke (OR=0.11, 95% CI 0.02–0.87, p=0.036). There was no significant difference in FH of vascular risk factors in MA patients compared to MO. CM patients were more likely to have a negative FH of stroke compared to other headache types, suggesting that CM is likely a neuronal disease rather than a vascular one.

Author information

Authors and Affiliations

Authors

Corresponding author

Correspondence to L. J. Ptácek.

Rights and permissions

Open Access This is an open access article distributed under the terms of the Creative Commons Attribution Noncommercial License ( https://creativecommons.org/licenses/by-nc/2.0 ), which permits any noncommercial use, distribution, and reproduction in any medium, provided the original author(s) and source are credited.

Reprints and Permissions

About this article

Cite this article

Yoon, G., Baggaley, S., Bacchetti, P. et al. Clinic–based study of family history of vascular risk factors and migraine. J Headache Pain 6, 412–416 (2005). https://doi.org/10.1007/s10194-005-0239-1

Download citation

  • Received:

  • Accepted:

  • Published:

  • Issue Date:

  • DOI: https://doi.org/10.1007/s10194-005-0239-1

Key words

  • Vascular risk factors
  • Stroke
  • Migraine