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  • Open Access

Systemic autonomic involvement in episodic cluster headache: a comparison between active and remission periods

  • 1Email author,
  • 1,
  • 1 and
  • 1
The Journal of Headache and Pain20056:196

  • Published:


In this study we compared systemic autonomic involvement in episodic cluster headache during active and silent periods. Seventeen patients were studied with sympathetic skin response, lying to standing test, Valsalva manoeuvre, deep breathing test and orthostatic hypotension evaluation. Each of them underwent these tests during active and silent periods. Values were then compared with normal controls. Our data show a parasympathetic, but not sympathetic, involvement. Moreover, this impairment seems to be “chronic”, as it persists beyond the active period.

Key words

  • Cluster headache
  • Autonomic tests
  • Vegetative nervous system


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