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Patients with headache and functional dyspepsia present meal–induced hypersensitivity of the stomach
The Journal of Headache and Pain volume 6, pages 223–226 (2005)
Abstract
Headache is a frequent feature of functional gastrointestinal disorders but there is no data on the responsible pathophysiological mechanism. The aim of this study was to verify whether alteration of post–prandial gastric tone or sensitivity might explain this association. Fourteen patients affected by functional dyspepsia (7 migraine without aura) and 7 healthy volunteers (HV) underwent gastric tone measurement in fasting condition and after the administration of a liquid meal by barostat. Gastric volume (GV) and accommodation were calculated as difference between mean post–prandial and mean fasting volume. Mean postprandial GV increase and fasting perception and discomfort threshold (DTh) were similar among the 3 groups. DTh after meal was lower in dyspeptic headache patients than in HV and dyspeptic without headache patients. Patients with migraine and functional dyspepsia may be characterised by meal-induced hypersensitivity of the stomach.
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Open Access This is an open access article distributed under the terms of the Creative Commons Attribution Noncommercial License ( https://creativecommons.org/licenses/by-nc/2.0 ), which permits any noncommercial use, distribution, and reproduction in any medium, provided the original author(s) and source are credited.
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Pucci, E., Di Stefano, M., Miceli, E. et al. Patients with headache and functional dyspepsia present meal–induced hypersensitivity of the stomach. J Headache Pain 6, 223–226 (2005). https://doi.org/10.1007/s10194-005-0191-0
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DOI: https://doi.org/10.1007/s10194-005-0191-0