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  1. Due to the high mortality and disability rate of intracranial hemorrhage, headache is not the main focus of research on cerebral arteriovenous malformation (AVM), so research on headaches in AVM is still scarc...

    Authors: Haibin Zhang, Heze Han, Li Ma, Ruinan Li, Zhipeng Li, Anqi Li, Kexin Yuan, Qinghui Zhu, Chengzhuo Wang, Yukun Zhang, Hongwei Zhang, Dezhi Gao, Geng Guo, Shuai Kang, Xun Ye, Youxiang Li…
    Citation: The Journal of Headache and Pain 2024 25:72
  2. There are no robust population-based Australian data on prevalence and attributed burden of migraine and medication-overuse headache (MOH) data. In this pilot cross-sectional study, we aimed to capture the par...

    Authors: Emma Foster, Zhibin Chen, Claire E Wakefield, Zanfina Ademi, Elspeth Hutton, Timothy J Steiner and Alessandro S Zagami
    Citation: The Journal of Headache and Pain 2024 25:71
  3. Recently, diagnostic criteria including a standardized MRI criterion were presented to identify patients suffering from idiopathic intracranial hypertension (IIH) proposing that IIH might be defined by two out...

    Authors: Stefan Macher, Wolfgang Marik, Nik Krajnc, Christoph Mitsch, Martin Michl, Nina Mueller, Klaus Novak, Sina Zaic, Christian Woeber, Berthold Pemp and Gabriel Bsteh
    Citation: The Journal of Headache and Pain 2024 25:70
  4. Calcitonin gene-related peptide (CGRP) is the most promising candidate to become the first migraine biomarker. However, literature shows clashing results and suggests a methodological source for such discrepan...

    Authors: Gabriel Gárate, Julio Pascual, Marta Pascual-Mato, Jorge Madera, María Muñoz-San Martín and Vicente González-Quintanilla
    Citation: The Journal of Headache and Pain 2024 25:69
  5. Acupuncture showed better improvement than sham acupuncture in reducing attack frequency of tension-type headache (TTH), but its effectiveness relative to first-line drugs for TTH is unknown, which impedes the...

    Authors: Qing-Feng Tao, Yan-Bing Huang, Lu Yuan, Yun-Zhou Shi, Di Qin, Kun Ye, Wen-Yan Peng, Chao-Rong Xie and Hui Zheng
    Citation: The Journal of Headache and Pain 2024 25:67
  6. Several studies have focused on the use of triptan and the risk of acute vascular events but the existence of such association is still debated and has never been quantified in patients over 65 years. To asses...

    Authors: Phuong Thao Tran, Maryse Lapeyre-Mestre, Baricault Berangere, Michel Lanteri-Minet, Aurore Palmaro, Anne Donnet and Joëlle Micallef
    Citation: The Journal of Headache and Pain 2024 25:68
  7. We have previously shown headache to be highly prevalent among adults in Saudi Arabia. Here we estimate associated symptom burden and impaired participation (impaired use of time, lost productivity and disenga...

    Authors: Mohammed Al Jumah, Ali M. Al Khathaami, Suleman Kojan, Andreas Husøy and Timothy J. Steiner
    Citation: The Journal of Headache and Pain 2024 25:66
  8. Despite recent advancements in migraine treatment, some patients continue to endure significant disease burden. Due to the controlled nature of randomized trials in migraine prevention, many real-world patient...

    Authors: Charles Argoff, Steven P. Herzog, Ryan M. Smith, Sameer V. Kotak, Liza Sopina, Yvonna Saltarska, Seema Soni-Brahmbhatt and Fawad A. Khan
    Citation: The Journal of Headache and Pain 2024 25:65
  9. Postdural puncture headache (PDPH) is an acknowledged consequence of procedures like lumbar punctures, epidural analgesia, and neurosurgical interventions. Persistence over more than three months, however has ...

    Authors: Ali Kapan, Thomas Waldhör, Tobias Schiffler, Jürgen Beck and Christian Wöber
    Citation: The Journal of Headache and Pain 2024 25:64
  10. Sexual dimorphism has been revealed for many neurological disorders including chronic pain. Prelicinal studies and post-mortem analyses from male and female human donors reveal sexual dimorphism of nociceptors...

    Authors: Shagun Singh, Caroline M. Kopruszinski, Moe Watanabe, David W. Dodick, Edita Navratilova and Frank Porreca
    Citation: The Journal of Headache and Pain 2024 25:63
  11. Chronic migraine (CM) negatively impacts the quality of life of 2 to 4% of pediatric patients. In adults, CM is frequently linked to medication overuse headache (MOH), but there is a much lower prevalence of M...

    Authors: Ilaria Frattale, Michela Ada Noris Ferilli, Fabiana Ursitti, Giorgia Sforza, Gabriele Monte, Martina Proietti Checchi, Samuela Tarantino, Luigi Mazzone, Massimiliano Valeriani and Laura Papetti
    Citation: The Journal of Headache and Pain 2024 25:61
  12. Migraine is a highly prevalent neurological disease with a substantial societal burden due to lost productivity. From a societal perspective, we assessed the cost-effectiveness of eptinezumab for the preventiv...

    Authors: Edward Griffin, Gawain Shirley, Xin Ying Lee, Susanne F. Awad, Alok Tyagi and Peter J. Goadsby
    Citation: The Journal of Headache and Pain 2024 25:59
  13. Migraine is a complex neurological disorder with significant heterogeneity in its clinical presentation and molecular mechanisms. Calcitonin gene-related peptide (CGRP) has emerged as a key player in migraine ...

    Authors: Alicia Alpuente, Victor J. Gallardo, Laila Asskour, Edoardo Caronna, Marta Torres-Ferrus and Patricia Pozo-Rosich
    Citation: The Journal of Headache and Pain 2024 25:58
  14. Phosphodiesterase 3 (PDE-3) inhibition have been implicated in the neurobiologic underpinnings of migraine. Considering the clinical similarities between migraine and persistent post-traumatic headache (PPTH),...

    Authors: Haidar M. Al-Khazali, Rune H. Christensen, Basit Ali Chaudhry, Anna G. Melchior, Messoud Ashina, Rami Burstein and Håkan Ashina
    Citation: The Journal of Headache and Pain 2024 25:56
  15. Rimegepant orally disintegrating tablet (ODT), an oral small-molecule calcitonin gene-related peptide receptor antagonist, is indicated for acute and preventive treatment of migraine in the United States and ...

    Authors: Shengyuan Yu, Aihong Guo, Zhen Wang, Jianguang Liu, Ge Tan, Qian Yang, Mingjie Zhang, Hasiyeti Yibulaiyin, Huisheng Chen, Yongbo Zhang, Robert Croop, Yanhui Sun, Yu Liu, Qian Zhao and Zhihong Lu
    Citation: The Journal of Headache and Pain 2024 25:57
  16. Patients with migraine often have poor sleep quality between and during migraine attacks. Furthermore, extensive research has identified photophobia as the most common and most bothersome symptom in individual...

    Authors: Nina Sharp, Mark J Burish, Kathleen B Digre, Jessica Ailani, Mahya Fani, Sophia Lamp and Todd J. Schwedt
    Citation: The Journal of Headache and Pain 2024 25:55
  17. Autonomic nervous system (ANS) testing has aided in our ability to evaluate autonomic dysfunction in migraine patients. We reviewed the literature in multiple databases which investigate ANS function in migrai...

    Authors: Antun R. Pavelić, Karin Zebenholzer and Christian Wöber
    Citation: The Journal of Headache and Pain 2024 25:54
  18. Visual snow syndrome is a disorder characterized by the combination of typical perceptual disturbances. The clinical picture suggests an impairment of visual filtering mechanisms and might involve primary and ...

    Authors: Antonia Klein, Sarah A. Aeschlimann, Frederic Zubler, Adrian Scutelnic, Franz Riederer, Matthias Ertl and Christoph J. Schankin
    Citation: The Journal of Headache and Pain 2024 25:53
  19. The Global Burden of Disease (GBD) study is increasingly well informed with regard to headache disorders, but sub-Saharan Africa (SSA) remains one of the large regions of the world with limited data directly d...

    Authors: Thierry Adoukonou, Mendinatou Agbetou, Eric Dettin, Oyene Kossi, Andreas Husøy, Hallie Thomas, Dismand Houinato and Timothy J Steiner
    Citation: The Journal of Headache and Pain 2024 25:52
  20. Chronic migraine is a highly debilitating condition that is often difficult to manage, particularly in the presence of medication overuse headache. Drugs targeting the calcitonin gene-related peptide (CGRP), o...

    Authors: Renato Oliveira, Raquel Gil-Gouveia and Francesca Puledda
    Citation: The Journal of Headache and Pain 2024 25:51
  21. The series of population-based studies conducted by the Global Campaign against Headache has, so far, included Pakistan and Saudi Arabia from the Eastern Mediterranean Region. The Maghreb countries of North Af...

    Authors: Najib Kissani, Latifa Adarmouch, Aboubacar Sidik Sidibe, Abderrahmane Garmane, Rachid Founoun, Mohamed Chraa, Hallie Thomas, Andreas Husøy and Timothy J Steiner
    Citation: The Journal of Headache and Pain 2024 25:49
  22. The Global Campaign against Headache is conducting a series of population-based studies to fill the large geographical gaps in knowledge of headache prevalence and attributable burden. One major region not unt...

    Authors: Guiovanna Quispe, Cesar Loza, Luis Limaco, Ruth Gallegos, Carlos Palomino, Ivett Cruz, Jacqueline Miranda, Liliana Rodriguez, Andreas Husøy and Timothy J Steiner
    Citation: The Journal of Headache and Pain 2024 25:48
  23. Migraine stands as a prevalent primary headache disorder, with prior research highlighting the significant involvement of oxidative stress and inflammatory pathways in its pathogenesis and chronicity. Existing...

    Authors: Yingyuan Liu, Zihua Gong, Deqi Zhai, Chunxiao Yang, Guangshuang Lu, Shuqing Wang, Shaobo Xiao, Chenhao Li, Ludan Chen, Xiaoxue Lin, Shuhua Zhang, Shengyuan Yu and Zhao Dong
    Citation: The Journal of Headache and Pain 2024 25:50
  24. We previously reported high prevalences of headache disorders among children (6–11 years) and adolescents (12–17 years) in Ethiopia. Here we provide data on headache-attributed burden collected contemporaneous...

    Authors: Yared Zenebe Zewde, Mehila Zebenigus, Hanna Demissie, Redda Tekle-Haimanot, Derya Uluduz, Tayyar Şaşmaz, Fatma Bozdag and Timothy J Steiner
    Citation: The Journal of Headache and Pain 2024 25:47
  25. To date, migraine is diagnosed exclusively based on clinical criteria, but fluid biomarkers are desirable to gain insight into pathophysiological processes and inform clinical management. We investigated the s...

    Authors: Marie Süße, Christine Kloetzer, Sebastian Strauß, Johanna Ruhnau, Lucas Hendrik Overeem, Merle Bendig, Juliane Schulze, Uwe Reuter, Antje Vogelgesang and Robert Fleischmann
    Citation: The Journal of Headache and Pain 2024 25:46
  26. As new migraine therapies emerge, it is crucial for measures to capture the complexities of health-related quality of life (HRQoL) improvement beyond improvements in monthly migraine day (MMD) reduction. Inves...

    Authors: Linus Jönsson, Susanne F. Awad, Stephane A. Regnier, Brian Talon, Steven Kymes, Xin Ying Lee and Peter J. Goadsby
    Citation: The Journal of Headache and Pain 2024 25:45
  27. Headache is a prevalent and debilitating symptom following traumatic brain injury (TBI). Large-scale, prospective cohort studies are needed to establish long-term headache prevalence and associated factors aft...

    Authors: Emilie Isager Howe, Nada Andelic, Cathrine Brunborg, Marina Zeldovich, Eirik Helseth, Toril Skandsen, Alexander Olsen, Silje C. R. Fure, Alice Theadom, Katrin Rauen, Benedikte Å. Madsen, Bram Jacobs, Joukje van der Naalt, Maria Carmela Tartaglia, Cathrine Elisabeth Einarsen, Gøril Storvig…
    Citation: The Journal of Headache and Pain 2024 25:44
  28. The objective of this analysis was to gain new insights into the patient characteristics and other factors associated with lasmiditan usage and clinical outcomes under conditions resembling the real-world sett...

    Authors: Mika Komori, Akichika Ozeki, Yuka Tanji, Eriko Kamiki, John H. Krege, Lily Qian Li, Shiho Suzuki, Mamoru Shibata and Takao Takeshima
    Citation: The Journal of Headache and Pain 2024 25:43
  29. Knowledge of headache prevalence, and the burdens attributable to headache disorders, remains incomplete in sub-Saharan Africa (SSA): reliable studies have been conducted only in Zambia (southern SSA) and Ethi...

    Authors: Callixte Kuate Tegueu, Anastase Dzudie Tamdja, Franklin Kom, Blaise Forgwa Barche, Peter Ebasone, Mélanie Magnerou, Paul Mbonda, Jacques Doumbe, Andreas Husøy, Hallie Thomas and Timothy J. Steiner
    Citation: The Journal of Headache and Pain 2024 25:42
  30. Knowledge of the prevalence and attributable burden of headache disorders in India is sparse, with only two recent population-based studies from South and East India. These produced conflicting results. A stud...

    Authors: Ashish Duggal, Debashish Chowdhury, Anand Krishnan, Ritvik Amarchand and Timothy J. Steiner
    Citation: The Journal of Headache and Pain 2024 25:41
  31. The reimbursement of erenumab in Spain and other European countries is currently restricted because of the cost of this novel therapy to patients with migraine who have experienced previous failures to traditi...

    Authors: Patricia Pozo-Rosich, José Luis Poveda, Carlos Crespo, María Martínez, José Manuel Rodríguez and Pablo Irimia
    Citation: The Journal of Headache and Pain 2024 25:40
  32. Anti-calcitonin gene-related peptide monoclonal antibodies (CGRPmAbs) have greatly changed migraine treatment options. In Japan, although CGRPmAb guidelines (≥ 4 monthly migraine days (MMDs) and ≥ 1 previous p...

    Authors: Tsubasa Takizawa, Keiko Ihara, Narumi Watanabe, Ryo Takemura, Nobuyuki Takahashi, Naoki Miyazaki, Mamoru Shibata, Keisuke Suzuki, Noboru Imai, Norihiro Suzuki, Koichi Hirata, Takao Takeshima and Jin Nakahara
    Citation: The Journal of Headache and Pain 2024 25:39
  33. The burden of migraine goes beyond the pain and associated symptoms. We aimed to describe the impact of migraine in healthcare resource utilization (HCRU), work productivity, and mood disorders, as well as its...

    Authors: David García-Azorín, Carlota Moya-Alarcón, Beatriz Armada and Margarita Sánchez del Río
    Citation: The Journal of Headache and Pain 2024 25:38
  34. The efficiency of The International Classification of Headache Disorders (ICHD-3) in reflecting patients’ disability has recently been questioned. This prompts consideration that clinical features beyond pain ...

    Authors: Tatiana Castro Zamparella, Mariela Carpinella, Mario Peres, Florencia Patricia Cuello, Pilar Maza, Melanie Van Gansen, Marcelo Filipchuk, Verónica Balaszczuk, Carolina Maldonado, Pablo Scarnato, Diego Conci Magris and Marco Lisicki
    Citation: The Journal of Headache and Pain 2024 25:37
  35. The upper cervical dorsal root ganglia (DRG) are important for the transmission of sensory information associated with the back of the head and neck, contributing to head pain. Calcitonin receptor (CTR)-based ...

    Authors: Tayla A. Rees, Zoe Tasma, Michael L. Garelja, Simon J. O’Carroll, Christopher S. Walker and Debbie L. Hay
    Citation: The Journal of Headache and Pain 2024 25:36
  36. Conventional, non-specific preventive migraine treatments often demonstrate low rates of treatment persistence due to poor efficacy or tolerability. Effective, well-tolerated preventive treatments are needed t...

    Authors: Paul Rizzoli, Michael J. Marmura, Jennifer Robblee, Jennifer McVige, Sara Sacco, Stephanie J. Nahas, Jessica Ailani, Rosa De Abreu Ferreira, Julia Ma, Jonathan H. Smith, Brett Dabruzzo and Messoud Ashina
    Citation: The Journal of Headache and Pain 2024 25:35
  37. Glymphatic system is an emerging pathway of removing metabolic waste products and toxic solutes from the brain tissue. It is made of a network of perivascular spaces, filled in cerebrospinal and interstitial f...

    Authors: Maria Grazia Vittorini, Aysenur Sahin, Antonin Trojan, Sevil Yusifli, Tamta Alashvili, Gonçalo V. Bonifácio, Ketevan Paposhvili, Viktoria Tischler, Christian Lampl and Simona Sacco
    Citation: The Journal of Headache and Pain 2024 25:34
  38. Energy metabolism disorders and neurogenic inflammation play important roles in the central sensitization to chronic migraine (CM). AMP-activated protein kinase (AMPK) is an intracellular energy sensor, and it...

    Authors: Guangshuang Lu, Shaobo Xiao, Fanchao Meng, Leyi Zhang, Yan Chang, Jinjing Zhao, Nan Gao, Wenjie Su, Xinghao Guo, Yingyuan Liu, Chenhao Li, Wenjing Tang, Liping Zou, Shengyuan Yu and Ruozhuo Liu
    Citation: The Journal of Headache and Pain 2024 25:29
  39. Both epidemiological and clinical studies have indicated that headache and sleep disturbances share a complex relationship. Although headache and sleep share common neurophysiological and anatomical foundation...

    Authors: Bozhi Li, Ya Cao, Huijuan Yuan, Zhe Yu, Shuai Miao, Chunxiao Yang, Zihua Gong, Wei Xie, Chenhao Li, Wenhao Bai, Wenjing Tang, Dengfa Zhao and Shengyuan Yu
    Citation: The Journal of Headache and Pain 2024 25:31
  40. Trigeminal nerve injury is one of the most serious complications in oral clinics, and the subsequent chronic orofacial pain is a consumptive disease. Increasing evidence demonstrates long non-coding RNAs (lncR...

    Authors: YaJing Liu, Fei Liu, YiKe Li, YueLing Li, YuHeng Feng, JiaShuo Zhao, Cheng Zhou, ChunJie Li, JieFei Shen and YanYan Zhang
    Citation: The Journal of Headache and Pain 2024 25:28
  41. The burden and disability associated with headaches are conceptualized and measured differently at patients’ and populations’ levels. At the patients’ level, through patient-reported outcome measures (PROMs); ...

    Authors: Marta Waliszewska-Prosół, Danilo Antonio Montisano, Mariola Antolak, Federico Bighiani, Francescantonio Cammarota, Ilaria Cetta, Michele Corrado, Keiko Ihara, Regina Kartamysheva, Igor Petrušić, Maria Magdalena Pocora, Tsubasa Takizawa, Gloria Vaghi, Paolo Martelletti, Barbara Corso and Alberto Raggi
    Citation: The Journal of Headache and Pain 2024 25:27
  42. Migraine is a disabling neurologic disease that can fluctuate over time in severity, frequency, and acute medication use. Harris Poll Migraine Report Card was a US population-based survey to ascertain quantifi...

    Authors: Amaal J. Starling, Roger Cady, Dawn C. Buse, Meghan Buzby, Charlie Spinale, Kathy Steinberg, Kevin Lenaburg and Steven Kymes
    Citation: The Journal of Headache and Pain 2024 25:26
  43. Migraine is a multiphasic neurovascular disorder, where headache can be succeeded by postdromal symptoms. However, there are limited research on postdromal symptoms. This study aimed to investigate the proport...

    Authors: Janu Thuraiaiyah, Håkan Ashina, Rune Häckert Christensen, Haidar M. Al-Khazali and Messoud Ashina
    Citation: The Journal of Headache and Pain 2024 25:25
  44. Prior research has shown that individual lifestyles were associated with migraine. Yet, few studies focused on combined lifestyles, particularly in Chinese populations. This cross-sectional study aimed to inve...

    Authors: Yunyang Deng, Harry Haoxiang Wang, Fei Wan Ngai, Dexing Zhang, Jing Qin, Xiangyan Chen and Yao Jie Xie
    Citation: The Journal of Headache and Pain 2024 25:24
  45. Medication overuse headache (MOH) was recently shown to be associated with leaky gut in rodents. We aimed to investigate whether chronic migraine (CM) patients with MOH have elevated lipopolysaccharide levels ...

    Authors: Doga Vuralli, Merve Ceren Akgor, Hale Gok Dagidir, Ozlem Gulbahar, Meltem Yalinay and Hayrunnisa Bolay
    Citation: The Journal of Headache and Pain 2024 25:23