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  1. With the rapid advances in the treatment of migraine attacks in the last few years, a number of non-specific anti-migraine drugs have been developed for clinical use. The most important class of drugs for the ...

    Authors: Virgilio Gallai† and Paola Sarchielli
    Citation: The Journal of Headache and Pain 2004 5(Suppl 2):127

    This article is part of a Supplement: Volume 5 Supplement 2

  2. Antidepressants are often used in the prophylaxis of chronic headaches, but their effectiveness is uncertain. A recent meta-analysis showed that antidepressants are effective in the treatment of chronic headac...

    Authors: Lorenzo Pinessi
    Citation: The Journal of Headache and Pain 2004 5(Suppl 2):125

    This article is part of a Supplement: Volume 5 Supplement 2

  3. The hypothesis that cortical hyperexcitability may play an important role in the physiopathology of migraine has lead to the therapeutic use of antiepileptic drugs in headache prophylaxis. Cortical hyperexcita...

    Authors: Girolamo Di Trapani, Daniele Mei, Catello Vollono, Alessandro Capuano and Diana Ferraro
    Citation: The Journal of Headache and Pain 2004 5(Suppl 2):124

    This article is part of a Supplement: Volume 5 Supplement 2

  4. Triptans are the treatment of choice for migraine sufferers with disabling attacks. However, the proportion of patients reporting side effects after any acute treatment may vary in regard to the method of asse...

    Authors: Michele Feleppa, Fred D. Sheftell, Luciana Ciannella, Amedeo D’Alessio, Giancarlo Apice, Nino N. Capobianco, Donato M. T. Saracino, Walter Di Iorio and Marcelo E. Bigal
    Citation: The Journal of Headache and Pain 2004 5(Suppl 2):123

    This article is part of a Supplement: Volume 5 Supplement 2

  5. Despite the pharmacokinetic differences among triptans and the variety of ways of administration, the clinical differences in everyday use of these drugs do not allow a largely accepted decisional tree. There ...

    Authors: Luigi A. Pini and Daria Brovia
    Citation: The Journal of Headache and Pain 2004 5(Suppl 2):122

    This article is part of a Supplement: Volume 5 Supplement 2

  6. The importance of the neuropsychological aspect in patients affected by tension headache is highlighted by different data in the literature as well as the results of a multicentric Italian study on comorbidity...

    Authors: Luciana Ciannella, Nino N. Capobianco, Amedeo D’Alessio and Michele Feleppa
    Citation: The Journal of Headache and Pain 2004 5(Suppl 2):121

    This article is part of a Supplement: Volume 5 Supplement 2

  7. Pharmacotherapeutic treatments for migraine have been documented for more than a century. Drugs that are effective in aborting an ongoing migraine attack exhibit a diversity of molecular mechanisms of action, ...

    Authors: Graeme Martin
    Citation: The Journal of Headache and Pain 2004 5(Suppl 2):120

    This article is part of a Supplement: Volume 5 Supplement 2

  8. Patients with chronic daily headache (CDH) are difficult to treat. A combination of general measures and specific pharmacological treatments is necessary. When possible, pharmacological management should be pl...

    Authors: Julio Pascual
    Citation: The Journal of Headache and Pain 2004 5(Suppl 2):118

    This article is part of a Supplement: Volume 5 Supplement 2

  9. Migraine is a highly prevalent headache disorder that has a substantial impact on the individual and society. Over the past decade, substantial advances in research have increased understanding of the pathophy...

    Authors: Marcelo E. Bigal and Richard B. Lipton
    Citation: The Journal of Headache and Pain 2004 5(Suppl 2):117

    This article is part of a Supplement: Volume 5 Supplement 2

  10. Several studies on patients observed in headache centers show an association between headache, including migraine, and arterial hypertension. As both these pathologies have an elevated prevalence in the genera...

    Authors: Marcello Fanciullacci, Massimo Alessandri, Francesco De Cesaris and Umberto Pietrini
    Citation: The Journal of Headache and Pain 2004 5(Suppl 2):116

    This article is part of a Supplement: Volume 5 Supplement 2

  11. The association between headache, especially migraine, and some immunomediated diseases, in particular autoimmune diseases, is well known. The evidence in favor of this association comes prevailingly from epid...

    Authors: Paola Sarchielli, Andrea Alberti, Francesca Coppola and Virgilio Gallai†
    Citation: The Journal of Headache and Pain 2004 5(Suppl 2):115

    This article is part of a Supplement: Volume 5 Supplement 2

  12. Placebo and placebo effect are important issues related to the drug therapy for clinical and scientific meanings. The rates of placebo may get as many as 50% for analgesic drugs in headache. The high answer to...

    Authors: Federica Galli, Barbara Riccio and Vincenzo Guidetti
    Citation: The Journal of Headache and Pain 2004 5(Suppl 2):113

    This article is part of a Supplement: Volume 5 Supplement 2

  13. Since it is extremely important to fully evaluate the psychological characteristics of young headache sufferers and their family circle, we have implemented a diagnostic therapeutic protocol arranged in a numb...

    Authors: Davide Moscato
    Citation: The Journal of Headache and Pain 2004 5(Suppl 2):112

    This article is part of a Supplement: Volume 5 Supplement 2

  14. Although migraine is a common complaint in childhood and adolescence, there is a lack of controlled clinical studies regarding treatment. In the young patient, the pharmacological approach should be preceded b...

    Authors: Beatrice Gallai, Giovanni Mazzotta and Paola Sarchielli
    Citation: The Journal of Headache and Pain 2004 5(Suppl 2):110

    This article is part of a Supplement: Volume 5 Supplement 2

  15. Children frequently suffer from migraine or tension-type headaches, and the headache pain not only interferes with a patient’s life but can affect his entire family. Headache management includes not only pharm...

    Authors: Francesca Tagliente, Francesca M. Ruju and Antonio Pascotto
    Citation: The Journal of Headache and Pain 2004 5(Suppl 2):109

    This article is part of a Supplement: Volume 5 Supplement 2

  16. We reviewed P300 and contingent negative variation (CNV) studies performed in migraine in order to identify their relevance in migraine and the role of neurophysiology in migraine. Publications available to us...

    Authors: Michele Feleppa, Walter Di Iorio and Donato M. T. Saracino
    Citation: The Journal of Headache and Pain 2004 5(Suppl 2):108

    This article is part of a Supplement: Volume 5 Supplement 2

  17. Headaches can be considered as a paradigm for the so-called “invisible” diseases; difficulties that headache patients encounter and complain from often relate more to the lack of understanding and communicatio...

    Authors: Stefania Radaelli, Matilde Leonardi* and Adriano Pessina
    Citation: The Journal of Headache and Pain 2004 5:104
  18. The objective was to provide objective imaging evidence of functional changes in brainstem structures involved in chronic daily headache (CDH). Over time, episodic migraine (EM) patients may develop CDH known ...

    Authors: Sheena K. Aurora, Vijaya Nagesh and K. Michael A. Welch
    Citation: The Journal of Headache and Pain 2004 5:103
  19. We wanted to document Turkish migraine sufferers’ unconventional therapy methods learnt from their social environment and discuss the historical background and possible action mechanisms of these methods. Unco...

    Authors: H. Macit Selekler and Sezer Komsuoğlu
    Citation: The Journal of Headache and Pain 2004 5:101
  20. The objective was to measure the cost of botulinum toxin type A (BTX-A) treatment of chronic tension-type headache. A prospective pharmaceutical costing analysis was completed in the Day Hospital of the Region...

    Authors: Fabio Palazzo, Francesco G. Mennini, Laura Fioravanti, Laura Piasini, Gabriella Coloprisco and Paolo Martelletti
    Citation: The Journal of Headache and Pain 2004 5:100
  21. The objective was to measure the impact of botulinum toxin type A (BTX-A) treatment on symptoms and medication utilisation patterns in patients with chronic tension-type headache. A retrospective chart analysi...

    Authors: Francesco S. Mennini, Laura Fioravanti, Laura Piasini, Fabio Palazzo, Gabriella Coloprisco and Paolo Martelletti
    Citation: The Journal of Headache and Pain 2004 5:99
  22. The objective was to examine the main genetic and environmental architecture of migraine in the Screening Across Lifetime of Twin (SALT) Study as a function of definition. We performed a quantitative genetic s...

    Authors: Dan A. Svensson, Elisabet Waldenlind, Karl Ekbom and Nancy L. Pedersen
    Citation: The Journal of Headache and Pain 2004 5:96
  23. The distinction between suffering and pain express the two faces of a disease that influence a patient quality of life. Suffering is a composite phenomenon. It implies moral elements, such as the question that...

    Authors: Matilde Leonardi, Elena Colombetti, Alessio Musio, Stefania Radaelli and Adriano Pessina
    Citation: The Journal of Headache and Pain 2004 5:88
  24. Owing to B. Ramazzini’s De morbis artificum diatriba, the 1700s may be considered as the century when occupational medicine was born. This paper considers Ramazzini’s treatise and some publications of the same ce...

    Authors: Giorgio Zanchin, Federico Mainardi, Filippo Dainese and Ferdinando Maggioni
    Citation: The Journal of Headache and Pain 2004 5:86
  25. SUNCT syndrome is a rare condition characterized by a short-lasting periorbital pain associated with autonomic symptoms. In this paper, a 50-year-old man with SUNCT syndrome is presented. Preexisting SUNCT syn...

    Authors: Sebnem Bicakci, Hacer Bozdemir, Yakup Sarica and Gamze Almak
    Citation: The Journal of Headache and Pain 2004 5:84
  26. After complaining of neck pain for 3 weeks, a 36-year-old man suddenly become quadriplegic during a massage session in a traditional Turkish bath. He was immediately transferred to hospital, where the initial ...

    Authors: Ahmet N. Kök, Omer S. Yildirim, Mehmet Kizilkaya, Ali F. Isik, Nasuhi E. Aydin and Talat Yurtman
    Citation: The Journal of Headache and Pain 2004 5:83
  27. A pair of identical twins with cluster headache is described. Monozygosity was confirmed by the identification of 14 DNA markers. In spite of harboring the same genes, the clinical picture presented by the twi...

    Authors: Pedro A. Kowacs, Elcio J. Piovesan, Lineu C. Werneck, Hudson Fameli, Marcos C. Lange and Salmo Raskin
    Citation: The Journal of Headache and Pain 2004 5:82
  28. We applied the second edition of the International Classification of Headache Disorders (ICHD-II) in 417 children (age range, 2–12 years) with chronic headaches attending a pediatric headache clinic. The initi...

    Authors: Marco A. Arruda, Carlos A. Bordini, Marcelo C. Ciciarelli and José G. Speciali
    Citation: The Journal of Headache and Pain 2004 5:81
  29. Seven oral triptans are available for treating acute migraine. We surveyed US migraine sufferers on the relative importance of treatment attributes for choosing among oral triptans. A multiattribute decision m...

    Authors: Richard B. Lipton, Joshua Liberman, F. Michael Cutrer, Peter J. Goadsby, Michel Ferrari, David W. Dodick, Douglas McCrory and Paul Williams
    Citation: The Journal of Headache and Pain 2004 5:80
  30. This randomized, multicenter, open-label, five-way crossover study was conducted to assess patients’ preference for tablet formulations of sumatriptan (50 mg and 100 mg), naratriptan (2.5 mg), rizatriptan (10 ...

    Authors: Carl Dahlöf, Martin Jones, Kim Davis, Jane Loftus and Reijo Salonen
    Citation: The Journal of Headache and Pain 2004 5:79
  31. Cluster headache (CH) is one of the most painful primitive headaches that exists. Since 1991, the subcutaneous administration of sumatriptan (SCS) in the treatment of acute attacks has proved to be rapid and e...

    Authors: Virginie Dousset, Virginie Chrysostome, Bruno Ruiz, S. Irachabal, Magalie Lafittau, Françoise Radat, Bruno Brochet and Patrick Henry
    Citation: The Journal of Headache and Pain 2004 5:78
  32. We performed a randomized, double-blind, placebo-controlled trial to determine the efficacy of botulinum toxin type A (BOTOX; Allergan) in treating frontal tension-type headache (TTH). A total of 40 patients a...

    Authors: Mimi S. Kokoska, Dee A. Glaser, Christine M. Burch and Christopher S. Hollenbeak
    Citation: The Journal of Headache and Pain 2004 5:77
  33. We describe a case of tramadol-related respiratory depression in a 69-year-old man, admitted to our hospital because of severe anemia and melena in the context of chronic renal failure and dialysis treatment. ...

    Authors: Consalvo Mattia, Sandro Mazzaferro, Flaminia Coluzzi and Marta Luzi
    Citation: The Journal of Headache and Pain 2004 5:76
  34. Several neurophysiological techniques are available for examining children with headache. The choice among them is made according to clinical features.

    Authors: Roberto Canitano and Vincenzo Guidetti
    Citation: The Journal of Headache and Pain 2004 5:75
  35. The widely used term chronic daily headache is a common denominator for a chronic headache with a daily occurrence but is not included in the former and in the revised versions of the IHS classification system...

    Authors: Rigmor Jensen and Lars Bendtsen
    Citation: The Journal of Headache and Pain 2004 5:74
  36. Physicians involved in care of migraine patients should make a considerable effort to educate themselves and their patients. It is fundamental that doctors, patients and their families understand the causes of...

    Authors: Pablo Irimia, Susana de la Riva and Eduardo Martínez-Vila
    Citation: The Journal of Headache and Pain 2004 5:67
  37. Although the prevalence of headache in the elderly is relevant, until now few studies have been conducted in patients over the age of 65 years. We analyzed the clinical charts of 4,417 consecutive patients ref...

    Authors: C. Lisotto, F. Mainardi, F. Maggioni, F. Dainese and G. Zanchin
    Citation: The Journal of Headache and Pain 2004 5:66
  38. We describe the electroencephalographic findings in nine pediatric migraineurs during the ictal phase of pain. We observed abnormal patterns on electroencephalography (EEG) in seven patients with migraine with...

    Authors: Francesco Pisani and Carlo Fusco
    Citation: The Journal of Headache and Pain 2004 5:64
  39. The pathogenesis of migraine headache is poorly understood but the trigeminovascular system seems to play an important role in it. The trigeminal nucleus caudalis is sensitised by noxious sensory stimuli, ofte...

    Authors: Elliot Shevel and Egilius H. Spierings
    Citation: The Journal of Headache and Pain 2004 5:62