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  1. Many findings relate migraine and cluster headaches to a genetic alteration, even if the site of the defect has not been identified. Some of these findings indicate an involvement of mitochondrial DNA, althoug...

    Authors: Brune M. Fusco and Mario Giacovazzo

    Citation: The Journal of Headache and Pain 2014 3:30100051

    Content type: Brief Report

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  2. Research has shown that inhalation of pure oxygen is effective in aborting cluster headache. This article advances the hypothesis that cooling is the critical ingredient behind the effectiveness of oxygen inha...

    Authors: Martha Sue McLeod, Frank Andrasik, Russel C. Packard and Bayard D. Miller

    Citation: The Journal of Headache and Pain 2014 3:30100033

    Content type: Original

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  3. We assessed the prevalence of a number of behavioral and somatic symptoms in women with migraine and investigated whether they were related to personality. In 46 women with migraine, record was taken of 26 sym...

    Authors: Franco Mongini, Maria Poma, Francesca Ibertis and Alexei Mossolov

    Citation: The Journal of Headache and Pain 2014 3:30100027

    Content type: Original

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  4. Idiopathic stabbing headache is a not well known type of pain, and few reports have described the disorder in juvenile age. We report a sample of 30 juvenile patients with clinical features of stabbing headach...

    Authors: Vincenzo Raieli, Giovanni Luca Eliseo, Michela La Vecchia, Girolama La Franca, Eleonora Pandolfi, Domenico Puma, Donatella Ragusa and Mario Eliseo

    Citation: The Journal of Headache and Pain 2014 3:30100021

    Content type: Review

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  5. Migraine is a common neurological condition affecting yearly 1%–10% of all men and 3%–20% of all women. Focal neurological symptoms (auras), most commonly visual and sensory, occur in 4% of migraine attacks. M...

    Authors: Lucilla Parnetti, Maurizio Paciaroni and Virgilio Gallai

    Citation: The Journal of Headache and Pain 2014 3:30100015

    Content type: Review

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  6. In recent years, we have seen exciting advances in the knowledge of mechanisms that underlie migraine. These have thus promoted investigations into new drugs for the management of acute migraine. The major go...

    Authors: Marcello Fanciullacci

    Citation: The Journal of Headache and Pain 2014 3:30100001

    Content type: EDITORIAL

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  7. SUNCT syndrome (shortlasting unilateral neuralgiform headache attacks with conjunctival injection and tearing) is a rare, debilitating headache that is difficult to be treated. We describe a SUNCT patient, in...

    Authors: Piero Meineri, Fiorella Mondino and Enzo Grasso

    Citation: The Journal of Headache and Pain 2002 3:00034

    Content type: BRIEF REPORT

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  8. The focus of this paper is the family factors associated with primary headache in children between 8 and 14 years. We studied the differences in the family ecology between 32 children with headaches and 32 he...

    Authors: Ursula Napoli, Vanna Axia and Pier Antonio Battistella

    Citation: The Journal of Headache and Pain 2002 3:00033

    Content type: ORIGINAL

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  9. Menstrual migraine (MM) pathogenesis has not yet been clarified, even though several hypotheses have been formulated. In the present research, we investigated cerebral blood flow in 15 patients with MM. Brain...

    Authors: Bašak Karakurum, Seniha Naldöken, Hülya Ortapamuk, Serap Üčler and Levent E. İnan

    Citation: The Journal of Headache and Pain 2002 3:00032

    Content type: ORIGINAL

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  10. The blockade of the greater occipital nerve (GON) has been used in the treatment of migraine without aura (MWOA), tension-type headache (TTH) and cervicogenic headache (CH). There have been only a few reports...

    Authors: Tansel Terzi, Bašak Karakurum, Serap Üçler, Levent E. İnan and Cankat Tulunay

    Citation: The Journal of Headache and Pain 2002 3:00031

    Content type: ORIGINAL

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  11. Little has been done to investigate the biochemical basis of chronic daily headache (CDH). Our group has recently demonstrated an increase in the cerebrospinal fluid (CSF) levels of nerve growth factor (NGF) ...

    Authors: Paola Sarchielli, Andrea Alberti, Beatrice Gallai, Francesca Coppola, Antonio Baldi, Ardesio Floridi and Virgilio Gallai

    Citation: The Journal of Headache and Pain 2002 3:00030

    Content type: ENRICO GREPPI AWARD

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  12. Current severity (intensity) grading in headache is based upon a 4-grade category scale that includes the zero grade. For ordinary scientific and practical work, a low-sensitivity scale may suffice. However, ...

    Authors: Ottar Sjaastad, T.A. Fredriksen, H.C. Petersen and L.S. Bakketeig

    Citation: The Journal of Headache and Pain 2002 3:00029

    Content type: SPECIAL ARTICLE

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  13. The objective of our study is to report the frequency and characteristics of cluster headache with aura among the population of patients with cluster headache treated in our outpatient neurology clinic. 254 p...

    Authors: Eva Martínez-Fernández, Roman Alberca, Pablo Mir, Emilio Franco, Enrique Montes and Pilar Lozano

    Citation: The Journal of Headache and Pain 2002 3:00026

    Content type: BRIEF REPORT

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  14. We examined the efficacy of physical therapy and adjunctive botulinum toxin type A (BTX-A) injections in the treatment of cervical headache. We performed a doubleblind, randomised, placebo-controlled study ov...

    Authors: Peter Schnider, Ecaterina Moraru, Marion Vigl, Christian Wöber, Daniela Földy, Joachim Maly, Christian Bittner, Peter Wessely and Eduard Auff

    Citation: The Journal of Headache and Pain 2002 3:00024

    Content type: ORIGINAL

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  15. Based on the knowledge that migraine and tension-type headache (TTH) are associated with reduced effectiveness at work and impairment of function in social roles, we studied the different influences that thes...

    Authors: Konstantinidos Vadikolias, Ioannis Heliopoulos, Grigorios Tripsianis, Athanasios Achtaropoulos, Elias Homsioglou, Nickolaos Artemis, Haritomeni Piperidou and Ioannis Milonas

    Citation: The Journal of Headache and Pain 2002 3:00023

    Content type: ORIGINAL

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  16. Twenty-three patients, aged 18‐66 years and suffering from migraine with or without aura, were randomly selected to receive either vigabatrin or matched placebo tablets first for 12 weeks in a double-blind cr...

    Authors: Karabi Ghose, Brian E. Niven and Dave Berry

    Citation: The Journal of Headache and Pain 2002 3:00022

    Content type: ORIGINAL

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  17. Cluster headache (CH) is the most frequent primary trigeminal autonomic cephalalgia (Goadsby, 2001). Clinical symptoms have been clearly identified and are described in the IHS classification. Cluster-like he...

    Authors: Pierric Giraud, Emmanuel Jouanneau, Françoise Borson-Chazot, Michel Lanteri-Minet and Guy Chazot

    Citation: The Journal of Headache and Pain 2002 3:00021

    Content type: REVIEW

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  18. The clinical questions posed by the advent of acute migraine-specific treatment (triptans) are on which patient to use specific treatment for migraine, and when in the attack to treat patients. Three strategi...

    Authors: Stewart J. Tepper, Alan M. Rapoport and Fred Sheftell

    Citation: The Journal of Headache and Pain 2002 3:00020

    Content type: REVIEW

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  19. Authors: Peter Hallas

    Citation: The Journal of Headache and Pain 2001 2:10020100.10194

    Content type:

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  20. Headache is the most frequent symptom in patients with cerebral venous thrombosis. However, patients presenting with headache due to cerebral venous thrombosis are uncommon. The association between oral contr...

    Authors: Enrico Tessitore, Claudio Schonauer, Francesco Fera and Alessandro Tessitore

    Citation: The Journal of Headache and Pain 2001 2:10020097.10194

    Content type: Case report

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  21. In this study, we evaluated, as far as clinical and functional aspects are concerned, the eventual and precocious improvement obtained with a combined orthognathic and surgical treatment on a group of 27 dysg...

    Authors: Carmen Mortellaro, Davide Giangrandi, Simonetta Gallo, Alessandro Leonardi and Marcella Pavese

    Citation: The Journal of Headache and Pain 2001 2:10020089.10194

    Content type: Original

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  22. The aim of this open study was to make a preliminary estimate of the efficacy and tolerability of intravenously administered magnesium sulfate (1 g) in comparison to subcutaneously administered sumatriptan in...

    Authors: Jasna Zidverc-Trajković, Aleksandra M. Pavlović, Zagorka Jovanović, Nadežda Šternić and Vladimir S. Kostić

    Citation: The Journal of Headache and Pain 2001 2:10020079.10194

    Content type: Original

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  23. The prevalence of patients suffering pain in hospital is high. This situation is censured during congresses on the study and treatment of pain, which highlight how little consideration the problem is given. O...

    Authors: Leonardo Trentin, Marco Visentin, Roberto de Marco and Elisabetta Zandolin

    Citation: The Journal of Headache and Pain 2001 2:10020073.10194

    Content type: Original

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  24. The involvement of nitric oxide (NO) in the pathophysiology of primary headaches was suggested by several authors during the last decade. Migraine, cluster headache, tension headache, and cervicogenic headach...

    Authors: Alessandra Zicari, Mario Giacovazzo and Paolo Martelletti

    Citation: The Journal of Headache and Pain 2001 2:10020067.10194

    Content type: Review

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  25. SUNCT is probably a distinct syndrome, although it shares some common features with cluster headache (CH): male sex preponderance, clustering of attacks, unilaterality of headache without sideshift, pain of n...

    Authors: Piotr Kruszewski, Juan A. Pareja, Ana B. Caminero and Ottar Sjaastad

    Citation: The Journal of Headache and Pain 2001 2:10020057.10194

    Content type: Review

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  26. The Italian Society for the Study of Headaches (SISC) published the first guidelines for diagnosis and treatment of migraine in 1993. In 2000, the Executive Committee of the SISC decided to provide updated dia...

    Authors: Virgilio Gallai and Paola Sarchielli

    Citation: The Journal of Headache and Pain 2001 2(Suppl 1):25

    Content type: THERAPY

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    This article is part of a Supplement: Volume 2 Supplement 1

  27. An association between migraine and menstruation can be ascertained by use of a diary for a minimum of three cycles. The pathophysiological and clinical peculiarities of menstrual migraine indicate that its ma...

    Authors: Franca Moschiano, Licia Grazzi, Domenico D’Amico, Ferdinando Schieroni and Gennaro Bussone

    Citation: The Journal of Headache and Pain 2001 2(Suppl 1):23

    Content type: THERAPY

    Published on:

    This article is part of a Supplement: Volume 2 Supplement 1

  28. Many drugs are now available for treating migraine attacks, including agents specifically indicated for this condition. Since 1990 sumatriptan, the first 5–HT1B,1D receptor agonist, was introduced and realized a ...

    Authors: Giorgio Zanchin, Filippo Dainese, Federico Mainardi and Ferdinando Maggioni

    Citation: The Journal of Headache and Pain 2001 2(Suppl 1):21

    Content type: THERAPY

    Published on:

    This article is part of a Supplement: Volume 2 Supplement 1

  29. The introduction of triptans, in the early 1990s, has improved the therapy for acute migraine attack, offering a new quality of life for those patients who suffer from this disabling neurological disorder. Epi...

    Authors: Dario Calderoni, Federica Galli and Vincenzo Guidetti

    Citation: The Journal of Headache and Pain 2001 2(Suppl 1):19

    Content type: THERAPY

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    This article is part of a Supplement: Volume 2 Supplement 1

  30. The current review providesa brief summary of the key pre–clinical and clinical characteristics of the triptans that might influence the choice of drug. Data from extensive clinical trials tentatively suggest ...

    Authors: Alan M. Rapoport and Stewart J. Tepper

    Citation: The Journal of Headache and Pain 2001 2(Suppl 1):17

    Content type: KEY NOTE LECTURE

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    This article is part of a Supplement: Volume 2 Supplement 1

  31. Migraine is currently considered to be a multifactorial disease in that it is modified by environmental and genetic factors and has a polygenic determination. Familial hemiplegic migraine (FHM), a subtype of m...

    Authors: Pasquale Montagna

    Citation: The Journal of Headache and Pain 2001 2(Suppl 1):15

    Content type: MIGRAINE AND PATHOPHYSIOLOGY

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    This article is part of a Supplement: Volume 2 Supplement 1

  32. We review the main electrophysiological abnormalities emerging from migraine studies and discuss them from the pathophysiological point of view. Considerations range from genetic aspects to the heterogeneous c...

    Authors: Giorgio Sandrini, Alberto Proietti Cecchini, Sonya Ivanova Hristova, Grazia Sances and Giuseppe Nappi

    Citation: The Journal of Headache and Pain 2001 2(Suppl 1):13

    Content type: MIGRAINE AND PATHOPHYSIOLOGY

    Published on:

    This article is part of a Supplement: Volume 2 Supplement 1

  33. GABA and glutamic acid are the main inhibitory and excitatory neurotransmitters of central nervous system. Among other functions they modulate the pain threshold in the CNS. For this reason it has been hypothe...

    Authors: Giovanni D’Andrea, Franco Granella, Morena Cataldini, Flavio Verdelli and Tiziana Balbi

    Citation: The Journal of Headache and Pain 2001 2(Suppl 1):11

    Content type: MIGRAINE AND PATHOPHYSIOLOGY

    Published on:

    This article is part of a Supplement: Volume 2 Supplement 1

  34. The theory that hypersensitivity of dopamine (DA) system is involved in the pathogenesis of migraine has been supported by various authors on the basis of clinical, pharmacological and, recently, genetic evide...

    Authors: Alessandra Cherchi, Erminia Stochino, Maria Paola Piccardi and Maria Del Zompo

    Citation: The Journal of Headache and Pain 2001 2(Suppl 1):9

    Content type: MIGRAINE AND PATHOPHYSIOLOGY

    Published on:

    This article is part of a Supplement: Volume 2 Supplement 1

  35. The periaqueductal gray matter (PAG) is at the center of a powerful descending antinociceptive neuronal network. We studied iron homeostasis in the PAG in episodic migraine patients between attacks and in chro...

    Authors: K. Michael A. Welch, Vijaya Nagesh, Sheena K. Aurora and Neil Gelman

    Citation: The Journal of Headache and Pain 2001 2(Suppl 1):7

    Content type: KEY NOTE LECTURE

    Published on:

    This article is part of a Supplement: Volume 2 Supplement 1

  36. Migraine is an heterogeneous disorder. Most patients are disabled both in work and in non–work activities. Different instruments to assess migraine–related disability have been developed. Among these, the migr...

    Authors: Domenico D’Amico, Susanna Usai, Licia Grazzi, Massimo Leone, Andrea Rigamonti, Chiara Nespolo and Gennaro Bussone

    Citation: The Journal of Headache and Pain 2001 2(Suppl 1):5

    Content type: MIGRAINE AND DISABILITY

    Published on:

    This article is part of a Supplement: Volume 2 Supplement 1

  37. Migraine is one of the most common neurological diseases afflicting 12% of general population but is poorly recognized and largely untreated. Migraine is a disabling disease with very high social costs as it a...

    Authors: Rosanna Cerbo, Marina Pesare, Cinzia Aurilia, Valeria Rondelli and Piero Barbanti

    Citation: The Journal of Headache and Pain 2001 2(Suppl 1):3

    Content type: MIGRAINE AND DISABILITY

    Published on:

    This article is part of a Supplement: Volume 2 Supplement 1