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  1. Content type: Original

    In this study, we evaluated, as far as clinical and functional aspects are concerned, the eventual and precocious improvement obtained with a combined orthognathic and surgical treatment on a group of 27 dysg...

    Authors: Carmen Mortellaro, Davide Giangrandi, Simonetta Gallo, Alessandro Leonardi and Marcella Pavese

    Citation: The Journal of Headache and Pain 2001 2:10020089.10194

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  2. Content type: Original

    The prevalence of patients suffering pain in hospital is high. This situation is censured during congresses on the study and treatment of pain, which highlight how little consideration the problem is given. O...

    Authors: Leonardo Trentin, Marco Visentin, Roberto de Marco and Elisabetta Zandolin

    Citation: The Journal of Headache and Pain 2001 2:10020073.10194

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  3. Content type: Review

    The involvement of nitric oxide (NO) in the pathophysiology of primary headaches was suggested by several authors during the last decade. Migraine, cluster headache, tension headache, and cervicogenic headach...

    Authors: Alessandra Zicari, Mario Giacovazzo and Paolo Martelletti

    Citation: The Journal of Headache and Pain 2001 2:10020067.10194

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  4. Content type: Review

    SUNCT is probably a distinct syndrome, although it shares some common features with cluster headache (CH): male sex preponderance, clustering of attacks, unilaterality of headache without sideshift, pain of n...

    Authors: Piotr Kruszewski, Juan A. Pareja, Ana B. Caminero and Ottar Sjaastad

    Citation: The Journal of Headache and Pain 2001 2:10020057.10194

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  5. Content type: KEY NOTE LECTURE

    DC MEG shifts, similar and complex in waveform, were observed in visually induced migraine with aura patients similar to spontaneous aura but not controls. Multiple cortical areas were activated in visually in...

    Authors: K. Michael A. Welch, Susan M. Bowyer, Sheena K. Aurora, John E. Moran and Norman Tepley

    Citation: The Journal of Headache and Pain 2001 2(Suppl 1):26

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    This article is part of a Supplement: Volume 2 Supplement 1

  6. Content type: THERAPY

    The Italian Society for the Study of Headaches (SISC) published the first guidelines for diagnosis and treatment of migraine in 1993. In 2000, the Executive Committee of the SISC decided to provide updated dia...

    Authors: Virgilio Gallai and Paola Sarchielli

    Citation: The Journal of Headache and Pain 2001 2(Suppl 1):25

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    This article is part of a Supplement: Volume 2 Supplement 1

  7. Content type: THERAPY

    Anticonvulsant drugs have been used in migraine prophylaxis since 1970. In recent years, new antiepileptic compounds have given rise to much interest in pain control. Migraine prophylaxis is still based on old...

    Authors: Fabio Frediani, Francesca Cominelli and Manlio Sgarzi

    Citation: The Journal of Headache and Pain 2001 2(Suppl 1):24

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    This article is part of a Supplement: Volume 2 Supplement 1

  8. Content type: THERAPY

    An association between migraine and menstruation can be ascertained by use of a diary for a minimum of three cycles. The pathophysiological and clinical peculiarities of menstrual migraine indicate that its ma...

    Authors: Franca Moschiano, Licia Grazzi, Domenico D’Amico, Ferdinando Schieroni and Gennaro Bussone

    Citation: The Journal of Headache and Pain 2001 2(Suppl 1):23

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    This article is part of a Supplement: Volume 2 Supplement 1

  9. Content type: THERAPY

    There is no consensus on which treatment strategy should be used in the acute therapy of migraine. A stratified care approach based on patient’s disabilty assessed by a valid instrument (the MIDAS questionnair...

    Authors: Sergio Genco, Domenico D’Amico, Franca Moschiano, Maria Pia Prudenzano, Paola Mosconi, Elena Floriani, Ferdinando Schieroni and Gennaro Bussone

    Citation: The Journal of Headache and Pain 2001 2(Suppl 1):22

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    This article is part of a Supplement: Volume 2 Supplement 1

  10. Content type: THERAPY

    Many drugs are now available for treating migraine attacks, including agents specifically indicated for this condition. Since 1990 sumatriptan, the first 5–HT1B,1D receptor agonist, was introduced and realized a ...

    Authors: Giorgio Zanchin, Filippo Dainese, Federico Mainardi and Ferdinando Maggioni

    Citation: The Journal of Headache and Pain 2001 2(Suppl 1):21

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    This article is part of a Supplement: Volume 2 Supplement 1

  11. Content type: THERAPY

    Despite the pharmacokinetic differences among triptans and the variety of ways of administration, the clinical differences in every day use of these drugs lack in an accepted decisional tree. In fact, there ar...

    Authors: Luigi Alberto Pini and Arrigo F. G. Cicero

    Citation: The Journal of Headache and Pain 2001 2(Suppl 1):20

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    This article is part of a Supplement: Volume 2 Supplement 1

  12. Content type: THERAPY

    The introduction of triptans, in the early 1990s, has improved the therapy for acute migraine attack, offering a new quality of life for those patients who suffer from this disabling neurological disorder. Epi...

    Authors: Dario Calderoni, Federica Galli and Vincenzo Guidetti

    Citation: The Journal of Headache and Pain 2001 2(Suppl 1):19

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    This article is part of a Supplement: Volume 2 Supplement 1

  13. Content type: THERAPY

    Since the observation that sumatriptan, the first triptan to be synthetized as a specific antimigraine compound, was able to block neurogenic inflammation (NI) in intra– and extracranial rat tissues, the exper...

    Authors: M. Gabriella Buzzi

    Citation: The Journal of Headache and Pain 2001 2(Suppl 1):18

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    This article is part of a Supplement: Volume 2 Supplement 1

  14. Content type: KEY NOTE LECTURE

    The current review providesa brief summary of the key pre–clinical and clinical characteristics of the triptans that might influence the choice of drug. Data from extensive clinical trials tentatively suggest ...

    Authors: Alan M. Rapoport and Stewart J. Tepper

    Citation: The Journal of Headache and Pain 2001 2(Suppl 1):17

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    This article is part of a Supplement: Volume 2 Supplement 1

  15. Content type: KEY NOTE LECTURE

    This paper reviews the literature of genetic epidemiology in primary headaches. Migraine without aura and migraine with aura are distinct disorders. Both are caused by a combination of genetic and environmental f...

    Authors: Michael Bjørn Russell

    Citation: The Journal of Headache and Pain 2001 2(Suppl 1):16

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    This article is part of a Supplement: Volume 2 Supplement 1

  16. Content type: MIGRAINE AND PATHOPHYSIOLOGY

    Migraine is currently considered to be a multifactorial disease in that it is modified by environmental and genetic factors and has a polygenic determination. Familial hemiplegic migraine (FHM), a subtype of m...

    Authors: Pasquale Montagna

    Citation: The Journal of Headache and Pain 2001 2(Suppl 1):15

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    This article is part of a Supplement: Volume 2 Supplement 1

  17. Content type: MIGRAINE AND PATHOPHYSIOLOGY

    Migraine, characterized by several autonomic disturbances both during and between attacks, suggests an involvement of the autonomic nervous system (ANS). To clarify the role of the ANS in migraine pathogenesis...

    Authors: Pietro Cortelli, Sabina Cevoli, Giuseppe Bonavina, Fabiola Magnifico and Giulia Pierangeli

    Citation: The Journal of Headache and Pain 2001 2(Suppl 1):14

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    This article is part of a Supplement: Volume 2 Supplement 1

  18. Content type: MIGRAINE AND PATHOPHYSIOLOGY

    We review the main electrophysiological abnormalities emerging from migraine studies and discuss them from the pathophysiological point of view. Considerations range from genetic aspects to the heterogeneous c...

    Authors: Giorgio Sandrini, Alberto Proietti Cecchini, Sonya Ivanova Hristova, Grazia Sances and Giuseppe Nappi

    Citation: The Journal of Headache and Pain 2001 2(Suppl 1):13

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    This article is part of a Supplement: Volume 2 Supplement 1

  19. Content type: MIGRAINE AND PATHOPHYSIOLOGY

    Modification in platelet activation and aggregation has been demonstrated in migraine patients both during and between attacks. A different pattern in the secretion of platelet products has also been observed ...

    Authors: Paola Sarchielli and Virgilio Gallai

    Citation: The Journal of Headache and Pain 2001 2(Suppl 1):12

    Published on:

    This article is part of a Supplement: Volume 2 Supplement 1

  20. Content type: MIGRAINE AND PATHOPHYSIOLOGY

    GABA and glutamic acid are the main inhibitory and excitatory neurotransmitters of central nervous system. Among other functions they modulate the pain threshold in the CNS. For this reason it has been hypothe...

    Authors: Giovanni D’Andrea, Franco Granella, Morena Cataldini, Flavio Verdelli and Tiziana Balbi

    Citation: The Journal of Headache and Pain 2001 2(Suppl 1):11

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    This article is part of a Supplement: Volume 2 Supplement 1

  21. Content type: MIGRAINE AND PATHOPHYSIOLOGY

    Nitric oxide (NO) probably plays an important role in the pathogenesis of migraine without aura (MWA). As the activation of NO–ergic cascade has been shown to be closely linked to cyclooxygenase pathway and to...

    Authors: Paolo Martelletti, Alessandra Zicari, Massimo Realacci, Giuseppe Fiore, Sergio De Filippis, Giuseppe Stirparo, Paola Denora, Maria Donata Solimeo, Cristina Rinaldi, Stefania Morrone and Mario Giacovazzo

    Citation: The Journal of Headache and Pain 2001 2(Suppl 1):10

    Published on:

    This article is part of a Supplement: Volume 2 Supplement 1

  22. Content type: MIGRAINE AND PATHOPHYSIOLOGY

    The theory that hypersensitivity of dopamine (DA) system is involved in the pathogenesis of migraine has been supported by various authors on the basis of clinical, pharmacological and, recently, genetic evide...

    Authors: Alessandra Cherchi, Erminia Stochino, Maria Paola Piccardi and Maria Del Zompo

    Citation: The Journal of Headache and Pain 2001 2(Suppl 1):9

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    This article is part of a Supplement: Volume 2 Supplement 1

  23. Content type: MIGRAINE AND PATHOPHYSIOLOGY

    Serotonin (5–HT) and serotonin receptors play an important role in migraine pathophysiology. Changes in platelet 5–HT content are not casually related, but they may reflect similar changes at a neuronal level....

    Authors: Massimo Leone, Andrea Rigamonti, Domenico D’Amico, Licia Grazzi, Susanna Usai and Gennaro Bussone

    Citation: The Journal of Headache and Pain 2001 2(Suppl 1):8

    Published on:

    This article is part of a Supplement: Volume 2 Supplement 1

  24. Content type: KEY NOTE LECTURE

    The periaqueductal gray matter (PAG) is at the center of a powerful descending antinociceptive neuronal network. We studied iron homeostasis in the PAG in episodic migraine patients between attacks and in chro...

    Authors: K. Michael A. Welch, Vijaya Nagesh, Sheena K. Aurora and Neil Gelman

    Citation: The Journal of Headache and Pain 2001 2(Suppl 1):7

    Published on:

    This article is part of a Supplement: Volume 2 Supplement 1

  25. Content type: MIGRAINE AND DISABILITY

    Migraine is associated with functional impairment. The migraine disability assessment (MIDAS) scale is a scientific instrument which captures headache–related disability. The Italian version of MIDAS was devel...

    Authors: Gennaro Bussone, Licia Grazzi, Susanna Usai, Paola Mosconi, Sergio Genco, Franco Michele Puca and Domenico D’Amico

    Citation: The Journal of Headache and Pain 2001 2(Suppl 1):6

    Published on:

    This article is part of a Supplement: Volume 2 Supplement 1

  26. Content type: MIGRAINE AND DISABILITY

    Migraine is an heterogeneous disorder. Most patients are disabled both in work and in non–work activities. Different instruments to assess migraine–related disability have been developed. Among these, the migr...

    Authors: Domenico D’Amico, Susanna Usai, Licia Grazzi, Massimo Leone, Andrea Rigamonti, Chiara Nespolo and Gennaro Bussone

    Citation: The Journal of Headache and Pain 2001 2(Suppl 1):5

    Published on:

    This article is part of a Supplement: Volume 2 Supplement 1

  27. Content type: MIGRAINE AND DISABILITY

    Although the genuine interest in measuring qualitative aspects of life has increased in the medical field together with our capability to transform patients’ subjective reports, opinions and ratings in standar...

    Authors: Giovanni Apolone and Paola Mosconi

    Citation: The Journal of Headache and Pain 2001 2(Suppl 1):4

    Published on:

    This article is part of a Supplement: Volume 2 Supplement 1

  28. Content type: MIGRAINE AND DISABILITY

    Migraine is one of the most common neurological diseases afflicting 12% of general population but is poorly recognized and largely untreated. Migraine is a disabling disease with very high social costs as it a...

    Authors: Rosanna Cerbo, Marina Pesare, Cinzia Aurilia, Valeria Rondelli and Piero Barbanti

    Citation: The Journal of Headache and Pain 2001 2(Suppl 1):3

    Published on:

    This article is part of a Supplement: Volume 2 Supplement 1

  29. Content type: MIGRAINE AND DISABILITY

    The 1988 International Headache Society (IHS) classification has greatly contributed to overcoming the obstacles that had made it difficult in the past to compare results of surveys on headache epidemiology. F...

    Authors: Gian Camillo Manzoni and Paola Torelli

    Citation: The Journal of Headache and Pain 2001 2(Suppl 1):2

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    This article is part of a Supplement: Volume 2 Supplement 1

  30. Content type: KEY NOTE LECTURE

    In the past decade researchers have become increasingly interested in quality of life as it pertains to headache, in particular migraine. A number of general health or well–being measures and migraine–specific...

    Authors: Frank Andrasik

    Citation: The Journal of Headache and Pain 2001 2(Suppl 1):1

    Published on:

    This article is part of a Supplement: Volume 2 Supplement 1

  31. Content type: Brief report

    The present case report underlies the importance of modifications in the characteristics of post-lumbar puncture headache, which led us to diagnose cerebral venous thrombosis in a 34-year-old woman affected b...

    Authors: Andrea Giorgetti, Maria Vittoria Calloni, Roberto Freschi, Giuseppe Mariani, Patrizia Perrone, Patrizia Secchi and Adriana Sermoni

    Citation: The Journal of Headache and Pain 2001 2:10020045.10194

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  32. Content type: Original Article

    Helicobacter pylori (H. pylori) has been recently associated with some organic and functional vascular disorders. In particular, our group found a high prevalence of H. pylori in patients affected by migraine an...

    Authors: Maurizio Gabrielli, Francesco Franceschi, Giuseppe Fiore, Marcello Candelli, Alessandro Armuzzi, Veronica Ojetti, Filippo Cremonini, Paolo Pola, Mario Giacovazzo and Antonio Gasbarrini

    Citation: The Journal of Headache and Pain 2001 2:10020039.10194

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  33. Content type: Original Article

    The aim our work was to study the personality profile and alexithymic syndrome (based on the analysis of seven specific markers) of primary headache patients through the Rorschach test. 240 headache patients ...

    Authors: Vincenzo Pizza, Daniele L.A. Spitaleri and Cesare Colucci d'Amato

    Citation: The Journal of Headache and Pain 2001 2:10020031.10194

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  34. Content type: Original Article

    Headache occurs frequently in acute ischemic stroke, but its frequency varies widely among different studies. We have prospectively studied headache features in patients with first-ever ischemic acute stroke ...

    Authors: Maurizio Paciaroni, Lucilla Parnetti, Paola Sarchielli and Virgilio Gallai

    Citation: The Journal of Headache and Pain 2001 2:10020025.10194

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  35. Content type: Review

    Sensitization of myofascial pain pathways may play an important role in the pathophysiology of chronic headache. Animal studies have shown that sensitization of pain pathways may be caused by associated with ...

    Authors: Messoud Ashina and Lars Bendtsen

    Citation: The Journal of Headache and Pain 2001 2:10020021.10194

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  36. Content type: Review

    Sumatriptan and the newer triptans (zolmitriptan, naratriptan, rizatriptan, eletriptan, almotriptan, frovatriptan and donitriptan) display high agonist activity at 5-HT1B and 5-HT1D receptors. Most triptans, but...

    Authors: Pramod R. Saxena and Peer Tfelt-Hansen

    Citation: The Journal of Headache and Pain 2001 2:10020003.10194

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  37. Content type: Original article

    Our purpose was to apply the Minnesota Multiphasic Personality Inventory (MMPI-2) to groups of women with different types of headache and facial pain. 117 women with tension-type headache (TTH), migraine (M),...

    Authors: Franco Mongini, Erika Barbalonga and Fabio Raviola

    Citation: The Journal of Headache and Pain 2000 1:00010105.10194

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  38. Content type:

    Chronic headache is often described but pooly understood regarding its mechanisms. We discuss the clinical presentation, differential diagnosis of chronic headache syndromes and treatment options. Patients pr...

    Authors: Maria Nicoladi and Federigo Sicuteri

    Citation: The Journal of Headache and Pain 2000 1(Suppl 1):0001S011.10194

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    This article is part of a Supplement: Volume 1 Supplement 1

  39. Content type:

    The mechanisms facilitating or prompting the chronicization of headache and the increased use of analgesics are still unknown and under debate. It is not clear whether the daily use of analgesics in chronic h...

    Authors: Luigi Alberto Pini and Giuliano Relja

    Citation: The Journal of Headache and Pain 2000 1(Suppl 1):0001S021.10194

    Published on:

    This article is part of a Supplement: Volume 1 Supplement 1

  40. Content type:

    T lymphocytes participate not only in immune responses but also in the development of several pathologic reactions. Human T helper cells, on the basis of the cytokines they release, fall into two phenotypes, ...

    Authors: Alessandra Zicari, Giuseppe Stirparo, Cristina Rinaldi, Mario Giacovazzo, Stefania Morrone and Paolo Martelletti

    Citation: The Journal of Headache and Pain 2000 1(Suppl 2):0001S177.10194

    Published on:

    This article is part of a Supplement: Volume 1 Supplement 2

  41. Content type:

    Molecular analysis of TNFA alleles in Italian subjects affected by migraine was performed in order to define the involfement of HLA region genes in migraine. No statistically significant differences in TNFA a...

    Authors: Monica Poscente, Gloria Brioli, Patrizia Lulli, Marina Morellini, Paolo Martelletti, Mario Giacovazzo and Simonetta Trabace

    Citation: The Journal of Headache and Pain 2000 1(Suppl 2):0001S169.10194

    Published on:

    This article is part of a Supplement: Volume 1 Supplement 2

  42. Content type:

    Molecular genetics offers a novel approach to the understanding and management of migraine since the disorder is known to have a strong genetic component. In recent studies, polymorphisms in the genes for dop...

    Authors: Stephen J. Peroutka

    Citation: The Journal of Headache and Pain 2000 1(Suppl 2):0001S147.10194

    Published on:

    This article is part of a Supplement: Volume 1 Supplement 2

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