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  1. In chronic migraine the central sensitisation and the changes of regional cerebral blood flow are mediated by nitric oxide (NO) and oxygen free radicals. Biofeedback is considered a preventive non–pharmacologi...

    Authors: I. Ciancarelli, M. G. Tozzi–Ciancarelli, C. Di Massimo, L. Olivieri and A. Carolei

    Citation: The Journal of Headache and Pain 2005 6:227

    Content type: PREVENTION OF CHRONIC HEADACHES

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  2. Chronic migraine (CM) is an invalidating condition affecting a significant population of headache sufferers, frequently associated with medication overuse headache (MOH). Controlled trials and guidelines for t...

    Authors: M. Trucco, P. Meineri and L. Ruiz

    Citation: The Journal of Headache and Pain 2005 6:225

    Content type: PREVENTION OF CHRONIC HEADACHES

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  3. Chronic migraine and transformed migraine are conditions with a progression from episodic to chronic headache, a disabling stage. During attack, cutaneous allodynia frequently occurs: it reflects sensitisation...

    Authors: M. Fanciullacci and F. De Cesaris

    Citation: The Journal of Headache and Pain 2005 6:224

    Content type: PREVENTION OF CHRONIC HEADACHES

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  4. A relationship between migraine and patent foramen ovale (PFO) has been observed in relatively small series of patients so far. Furthermore, the exact mechanism underlying such an association remains unknown. ...

    Authors: G. Dalla Volta, M. Guindani, P. Zavarise, S. Griffini, A. Pezzini and A. Padovani

    Citation: The Journal of Headache and Pain 2005 6:223

    Content type: HEADACHE: THERAPEURIC CHOICES

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  5. The authors discuss clinical and international experience about botulinum toxins (BTX types A and B) in headache treatment. Data from literature suggest good results for the treatment of tensiontype headache, ...

    Authors: M. Porta and M. Camerlingo

    Citation: The Journal of Headache and Pain 2005 6:222

    Content type: HEADACHE: THERAPEURIC CHOICES

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  6. We conducted a study on 367 patients (86% female, 14% male; mean age 37±15 years) suffering from migraine with and without aura and chronic tension–type headache to evaluate the incidence of weight gain, an un...

    Authors: F. Maggioni, S. Ruffatti, F. Dainese, F. Mainardi and G. Zanchin

    Citation: The Journal of Headache and Pain 2005 6:221

    Content type: HEADACHE: THERAPEURIC CHOICES

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  7. Sumatriptan is a selective agonist of 5HT1 (1B/1D) receptors, which has proved to be effective and safe for the acute treatment of migraine attacks. Nevertheless, its use by migraine sufferers is still limited...

    Authors: E. Sternieri, D. Pinetti, C. P. R. Coccia, S. Leone, A. Bertolini and A. Ferrari

    Citation: The Journal of Headache and Pain 2005 6:220

    Content type: HEADACHE: THERAPEURIC CHOICES

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  8. The cost–benefit and the risk–benefit ratios are two of the most relevant items in ongoing health organisation procedures. The choice of a new or an old therapeutic treatment depends on a number of factors and...

    Authors: L. A. Pini, M. M. Cainazzo and D. Brovia

    Citation: The Journal of Headache and Pain 2005 6:219

    Content type: HEADACHE: THERAPEUTIC CHOICES

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  9. The impact of migraine headaches is one of the major public health problems in several industrialised countries, with many patients reporting frequent and significant disability. Previous studies have assessed...

    Authors: R. Iannacchero, U. Cannistrà, A. La Vitola, F. Peltrone and E. De Caro

    Citation: The Journal of Headache and Pain 2005 6:218

    Content type: HEADACHE AND CONTINUITY IN HEALTH CARE

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  10. The continuous care of headache patients, from headache centres to general practice, is a managerial problem that is still unsolved in Italy. In fact, if on the one hand patients do not usually go to headache ...

    Authors: G. B. La Pegna, F. Brighina, V. Saporito, A. Aloisio, C. Morreale and A. D’Agati

    Citation: The Journal of Headache and Pain 2005 6:217

    Content type: HEADACHE AND CONTINUITY IN HEALTH CARE

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  11. Medication–overuse headache (MOH) is one of the headache forms that most frequently prompts patients to consult a specialist headache centre. The prevaence of this form in the general population is approximate...

    Authors: G. Sances, N. Ghiotto, M. Loi, E. Guaschino, E. Marchioni, T. Catarci and G. Nappi

    Citation: The Journal of Headache and Pain 2005 6:216

    Content type: HEADACHE AND CONTINUITY IN HEALTH CARE

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  12. Migraine is a complex pathology and it should be regarded as a disease evolving during the lifetime along with other comorbid conditions. Migraine susceptibility may be unmasked by exogenous substances and the...

    Authors: M. G. Buzzi, D. Cologno and R. Formisano

    Citation: The Journal of Headache and Pain 2005 6:215

    Content type: HEADACHE AND CONTINUITY IN HEALTH CARE

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  13. To evaluate the influence of psychometric variables on the “repeater” phenomenon in an emergency department, 15 “repeaters” and 27 outpatient migraineurs were recruited. All patients were submitted to the Beck...

    Authors: V. Villani, G. Bruti, C. Mostardini, F. Di Stani, L. Scattoni, D. Dugoni, N. Vanacore and R. Cerbo

    Citation: The Journal of Headache and Pain 2005 6:214

    Content type: HEADACHE IN THE EMERGENCY ROOM

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  14. The objective was to study the demographics, diagnostic procedures and therapies employed in order to provide guidelines to Emergency Department (ED) physicians. A six–month retrospective analysis of the recor...

    Authors: G. Relja, A. Granato, F. Capozzoli, C. Maggiore, M. Catalan, G. Pizzolato, W. Zalukar, V. Livia, S. Gregorutti and M. Zorzon

    Citation: The Journal of Headache and Pain 2005 6:213

    Content type: HEADACHE IN THE EMERGENCY ROOM

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  15. Although cluster headache (CH) is considered one of the most distinctive and painful primary headache disorders in clinical practice because of the brevity of each attack, its management is not always ergonomi...

    Authors: F. Di Sabato and M. Giacovazzo

    Citation: The Journal of Headache and Pain 2005 6:212

    Content type: HEADACHE IN THE EMERGENCY ROOM

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  16. Headache is one of the most common reported complaints in the general adult population and it accounts for between 1% and 3% of admissions to an Emergency Department (ED). The overwhelming majority of patients...

    Authors: R. Cerbo, V. Villani, G. Bruti, F. Di Stani and C. Mostardini

    Citation: The Journal of Headache and Pain 2005 6:210

    Content type: HEADACHE IN THE EMERGENCY ROOM

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  17. The prevalence and the clinical features of chronic daily headache (CDH) were studied in 968 children and adolescents observed during a period of one year in the Headache Centre of the Anna Meyer Paediatric Ho...

    Authors: C. Scalas and L. Calistri

    Citation: The Journal of Headache and Pain 2005 6:209

    Content type: HEADACHE IN CHILDHOOD AND ADOLESCENCE

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  18. The onset of post-traumatic headache occurs frequently in children, where it is often caused by severe head injuries, therefore, it is part of a post–traumatic syndrome, rather than of an independent headache ...

    Authors: D. Moscato, M. I. Peracchi, G. Mazzotta, L. Savi and P. A. Battistella

    Citation: The Journal of Headache and Pain 2005 6:208

    Content type: HEADACHE IN CHILDHOOD AND ADOLESCENCE

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  19. The aim of the study was to determine the frequency of clinical allodynia, osmophobia and red ear syndrome in a young population. Medical records of the children admitted for headache between 1 December 2004 a...

    Authors: V. Raieli, E. Pandolfi, M. La Vecchia, D. Puma, A. Calò, A. Celauro and D. Ragusa

    Citation: The Journal of Headache and Pain 2005 6:205

    Content type: HEADACHE IN CHILDHOOD AND ADOLESCENCE

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  20. Several epidemiological studies have shown the presence of comorbidity between various types of sleep disorders and different headache subtypes. Migraine without aura is a sensitive risk factor for disorders o...

    Authors: M. Carotenuto, V. Guidetti, F. Ruju, F. Galli, F. R. Tagliente and A. Pascotto

    Citation: The Journal of Headache and Pain 2005 6:204

    Content type: HEADACHE IN CHILDHOOD AND ADOLESCENCE

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  21. The Italian headache disorders website (www.cefalea.it) was launched in 1999 by the CIRNA foundation in partnership with Al.Ce, which is a lay association and member of the World Headache Alliance. In 2004, the w...

    Authors: P. Rossi, G. Sances and G. Nappi

    Citation: The Journal of Headache and Pain 2005 6:203

    Content type: HEADACHES, PHYSICIANS AND PATIENTS

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  22. The social perception of headache, everywhere at low levels in industrialised countries, becomes totally absent in developing ones. Headache disorders came into the World Health Organization’s strategic priori...

    Authors: P. Martelletti, R. T. Haimanot, M. J. A. Lainez, A. M. Rapoport, K. Ravishankar, F. Sakai, S. D. Silberstein, M. Vincent and T. J. Steiner

    Citation: The Journal of Headache and Pain 2005 6:202

    Content type: HEADACHES, PHYSICIANS AND PATIENTS

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  23. Clinical observations show that migraine attacks have a seasonal, menstrual and circadian timing, suggesting a role of chronobiological mechanisms and their alterations in the disease, but little experimental ...

    Authors: S. Gori, N. Morelli, M. Maestri, M. Fabbrini, E. Bonanni and L. Murri

    Citation: The Journal of Headache and Pain 2005 6:201

    Content type: PSYCHOBIOLOGICAL ASPECTS OF HEADACHES

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  24. The internal working model on attachment dimensions changes with significant emotional experiences. The purpose of this study was to evaluate if and how the internal working models correlate with primary heada...

    Authors: L. Savi, R. Buccheri, A. Tambornini, P. De Martino, C. Albasi and L. Pinessi

    Citation: The Journal of Headache and Pain 2005 6:200

    Content type: PSYCHOBIOLOGICAL ASPECTS OF HEADACHES

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  25. The aim of the study was to estimate the occurrence of mood, anxiety and disability disorders in 300 patients affected by chronic daily headache and MOH, who were observed for a 16–month period in our centre. ...

    Authors: S. De Filippis, E. Salvatori, G. Coloprisco and P. Martelletti

    Citation: The Journal of Headache and Pain 2005 6:199

    Content type: PSYCHOBIOLOGICAL ASPECTS OF HEADACHE

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  26. The purpose of this work was to investigate: (1) the differences in temperament and character between 49 women with migraine and 49 controls using the Temperament and Character Inventory (TCI), and (2) the ext...

    Authors: F. Mongini, S. Fassino, E. Rota, A. Deregibus, M. Levi, D. Monticone and G. Abbate–Daga

    Citation: The Journal of Headache and Pain 2005 6:198

    Content type: PSYCHOBIOLOGICAL ASPECTS OF HEADACHES

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  27. Recent investigations documented that the prevalence of right–to–left shunt (RLS) in patients with migraine with aura (MA) is significantly higher than in healthy controls and similar to prevalence of RLS in y...

    Authors: N. Morelli, S. Gori, G. Cafforio, S. Gallerini, F. Baldacci, G. Orlandi and L. Murri

    Citation: The Journal of Headache and Pain 2005 6:197

    Content type: TACs AND CRANIAL NEURALAGIA

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  28. In this study we compared systemic autonomic involvement in episodic cluster headache during active and silent periods. Seventeen patients were studied with sympathetic skin response, lying to standing test, V...

    Authors: Piero Meineri, Gianpaolo Pellegrino, Maria Gabriella Rosso and Enzo Grasso

    Citation: The Journal of Headache and Pain 2005 6:196

    Content type: TACS AND CRANIAL NEURALAGIA

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  29. Trigeminal neuralgia is universally considered the neuropathic facial pain most and best known in medical practice. We propose a short review on trigeminal neuralgia reporting its main clinical aspects, unsolv...

    Authors: A. Truini, F. Galeotti and G. Cruccu

    Citation: The Journal of Headache and Pain 2005 6:195

    Content type: TACs AND CRANIAL NEURALAGIA

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  30. Up to a few years ago, cluster headache (CH) was not thought to be an inherited disorder. However, several recent studies have suggested that genetic factors play a role in the disease. Genetic epidemiological...

    Authors: L. Pinessi, I. Rainero, C. Rivoiro, E. Rubino and S. Gallone

    Citation: The Journal of Headache and Pain 2005 6:194

    Content type: TACs AND CRANIAL NEURALAGIA

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  31. The presence of significant and confounding psychiatric comorbidity is greater in patients attending headache clinics than in headache patients from the general population. The frequent comorbidity of headache...

    Authors: M. Savarese, M. Guazzelli, M. P. Prudenzano, M. Carnicelli, M. Rossi, V. Cardinali, S. Genco, P. Lamberti and P. Livrea

    Citation: The Journal of Headache and Pain 2005 6:193

    Content type: HEADACHE: CLINICAL AND COMORBIDITY ASPECTS

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  32. To explore the relationship between the side of pain during attacks and psychopathological features in strictly unilateral migraine, we recruited 35 patients affected by migraine with and/or without aura diagn...

    Authors: D. Cologno, M. G. Buzzi, G. A. Carlesimo, P. Cicinelli, A. Costa, L. Fadda, R. Formisano, B. Marconi, S. Pero and C. Caltagirone

    Citation: The Journal of Headache and Pain 2005 6:192

    Content type: HEADACHE: CLINICAL AND COMORBIDITY ASPECTS

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  33. Headache is a frequent feature of functional gastrointestinal disorders but there is no data on the responsible pathophysiological mechanism. The aim of this study was to verify whether alteration of post–pran...

    Authors: E. Pucci, M. Di Stefano, E. Miceli, G. R. Corazza, G. Sandrini and G. Nappi

    Citation: The Journal of Headache and Pain 2005 6:191

    Content type: HEADACHE: CLINICAL AND COMORBIDITY ASPECTS

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  34. Literature data concerning the comorbidity of migraine and hypertension are conflicting and lacking in consistency [1–4]. This study was designed to evaluate the distribution of hypertension in a sample of mig...

    Authors: M. P. Prudenzano, C. Monetti, L. Merico, V. Cardinali, S. Genco, P. Lamberti and P. Livrea

    Citation: The Journal of Headache and Pain 2005 6:190

    Content type: HEADACHE: CLINICAL AND COMORBIDITY ASPECTS

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  35. Migraine is a highly prevalent and disabling disease that is substantially undiagnosed in primary care. Recently, the ID Migraine, a self–administered questionnaire, was shown to be a valid and reliable screen...

    Authors: F. Brighina, G. Salemi, B. Fierro, A. Gasparro, G. Balletta, A. Aloisio, G. La Pegna, G. Randisi, V. Saporito, G. Calagna, F. Lanaia and R. Morana

    Citation: The Journal of Headache and Pain 2005 6:189

    Content type: ICHD-II EVALUATION AND PROPOSALS

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  36. This study evaluates osmophobia (defined as an unpleasant perception, during a headache attack, of odours that are non–aversive or even pleasurable outside the attacks) in connection with the diagnosis of prim...

    Authors: G. Zanchin, F. Dainese, F. Mainardi, E. Mampreso, C. Perin and F. Maggioni

    Citation: The Journal of Headache and Pain 2005 6:188

    Content type: ICHD-II EVALUATION AND PROPOSALS

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  37. Medication overuse headache (MOH) is a clinically important entity and it is now well documented that the regular use of acute symptomatic medication by people with migraine or tensiontype headache increases t...

    Authors: P. Calabresi and L. M. Cupini

    Citation: The Journal of Headache and Pain 2005 6:184

    Content type: PATHOPHYSIOLOGY OF HEADACHES

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  38. A reduced habituation of averaged laser–evoked potential (LEP) amplitudes was previously found in migraine patients. The aim of the present study was to assess the habituation of single LEP responses and pain ...

    Authors: M. de Tommaso, G. Libro, M. Guido, L. Losito, P. Lamberti and P. Livrea

    Citation: The Journal of Headache and Pain 2005 6:183

    Content type: PATHOPHYSIOLOGY OF HEADACHES

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  39. The study of CNS painmodulating pathways has led to important discoveries about the role of central nociceptive structures such as PAG and hypothalamus in the pathophysiology of episodic and chronic primary he...

    Authors: P. Rossi, M. Serrao, A. Perrotta, F. Pierelli, G. Sandrini and G. Nappi

    Citation: The Journal of Headache and Pain 2005 6:182

    Content type: PATHOPHYSIOLOGY OF HEADACHES

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  40. Migraine without aura (MO) and migraine with aura (MA) are disorders involving multiple environmental and genetic factors. The A/G polymorphism located within exon 1 of the gene encoding the cytotoxic T lympho...

    Authors: P. Lulli, S. Trabace, M. Morellini, G. Cicciarelli, G. Coloprisco, M. Piane, S. De Filippis, P.G. Santi, O. Avramakou, E. Ferlicca and P. Martelletti

    Citation: The Journal of Headache and Pain 2005 6:181

    Content type: Genetics

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  41. We examined the distribution of HLA–DRB1 alleles in a cohort of 255 Italian migraine patients and in a control group of 325 healthy subjects. The frequency of DRB1*12 allele was found to be significantly reduced ...

    Authors: I. Rainero, E. Fasano, E. Rubino, C. Rivoiro, W. Valfrè, S. Gallone, L. Savi, S. Gentile, R. Lo Giudice, P. De Martino, A. M. Dall’Omo and L. Pinessi

    Citation: The Journal of Headache and Pain 2005 6:180

    Content type: Genetics

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  42. In the present work, we report that the functional serotonin transporter gene promoter (5–HTTLPR) polymorphism is involved in migraine pathogenesis. The distribution of 5–HTTLPR genotypes was significantly dif...

    Authors: B. Borroni, C. Brambilla, P. Liberini, R. Rao, S. Archetti, S. Gipponi, G. Dalla Volta and A. Padovani

    Citation: The Journal of Headache and Pain 2005 6:179

    Content type: Genetics

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  43. Numerous candidate genes for migraine have been proposed on the basis of their possible functional role in its pathogenesis. Genetic polymorphisms have been evaluated in association studies, some of which have...

    Authors: V. Lisi, G. Garbo, F. Miccichè, A. Stecca, S. Terrazzino, M. Franzoi, E. Tripoli, M. Clementi, A. Leon and P. A. Battistella

    Citation: The Journal of Headache and Pain 2005 6:178

    Content type: Genetics

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  44. Chronic daily headache (CDH) is a heterogeneous group of headaches that includes primary and secondary varieties. Primary CDH is a frequent entity that probably affects 4–5% of the population. It can be subdiv...

    Authors: Miguel J. A. Láinez

    Citation: The Journal of Headache and Pain 2005 6:177

    Content type: KEY NOTE LECTURE

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  45. Most women with migraine improve during pregnancy. Some women have their first attack. Migraine often recurs postpartum and can begin for the first time. Drugs are commonly used during pregnancy despite insuff...

    Authors: Stephen D. Silberstein

    Citation: The Journal of Headache and Pain 2005 6:176

    Content type: KEY NOTE LECTURE

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