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Fig. 1 | The Journal of Headache and Pain

Fig. 1

From: The effect of Lu AG09222 on PACAP38- and VIP-induced vasodilation, heart rate increase, and headache in healthy subjects: an interventional, randomized, double-blind, parallel-group, placebo-controlled study

Fig. 1

Study design. aKey endpoints assessed at 120 min are: change in STA (primary outcome) and RA diameter (measured by high-resolution ultrasonography), change in heart rate, and change in facial blood flow (measured by speckle contrast imager). PACAP38, pituitary adenylate cyclase-activating polypeptide 38; RA, radial artery; STA, superficial temporal artery; VIP, vasoactive intestinal peptide

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