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Table 6 Regression model for dichotomous outcomes (50 studies)

From: The temporal trend of placebo response in migraine prevention from 1990 to 2021: a systematic literature review and meta-analysis with regression

Covariate

Coefficient

95% Confidence Interval

P-value

Constant

-244.1

-2103.0 to 1614.9

0.792

Year (per year)

0.2

-0.7 to 1.1

0.682

Age (per year)

-2.4

-4.0 to -0.9

0.003

% Female (per 0.01 increase)

-0.1

-1.0 to 0.7

0.777

Cochrane Level of Bias

 Low (reference)

0

  

 Some

-9.8

-25.3 to 5.8

0.213

 High

-11.0

-35.9 to 13.9

0.377

Route

 Injection (reference)

0

  

 Oral

6.4

-4.8 to 17.6

0.253

 IV

11.5

1.5 to 21.4

0.025

  1. Abbreviations: IV Intravenous