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Fig. 3 | The Journal of Headache and Pain

Fig. 3

From: Descending serotonergic modulation from rostral ventromedial medulla to spinal trigeminal nucleus is involved in experimental occlusal interference-induced chronic orofacial hyperalgesia

Fig. 3

Delayed REOI, but not persistent EOI, increased the concentration of 5-HT in the Sp5. A, B The calibration curve of 5-HT and 5-HIAA concentration fitted by the detection of standard 5-HT and 5-HIAA, respectively, at various concentrations. C The 5-HT concentration was increased in REOI rats. D The 5-HIAA concentration was decreased in REOI rats. E The turnover rate was reduced in REOI rats. F The total concentration of 5-HT and 5-HIAA was not changed in both REOI and PEOI rats. n = 4 for each group. Results represent mean ± SD; one-way ANOVA, followed by Tukey’s multiple-comparison test

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The Journal of Headache and Pain

ISSN: 1129-2377

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