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Table 1 Participants’ demographics and clinical characteristics

From: Brain structure and cortical activity changes of new daily persistent headache: multimodal evidence from MEG/sMRI

 

Healthy Controls (n = 37)

NDPH (n = 28)

p-value

Age, years

33.00 (25.50, 43.50)

33.00 (17.00, 59.00)

0.926

Sex (male/female)

16/21 (43.24/56.76%)

14/14 (50.00/50.00%)

0.588

BMI (kg/m2)

22.45 ± 3.04

24.45 ± 3.88

0.023

Headache laterality, n (%)

    Unilateral

NA

10 (35.71%)

NA

    Bilateral

NA

18 (64.29%)

NA

Location of headache, n (%)

    Frontal region

NA

9 (32.14%)

NA

    Temporal region

NA

15 (53.57%)

NA

    Parietal region

NA

10 (35.71%)

NA

    Occipital region

NA

5 (17.86%)

NA

    Periorbital region

NA

1 (3.57%)

NA

    Nausea, vomiting, n (%)

NA

2 (7.14%)

NA

    Photophobia, n (%)

NA

11 (39.28%)

NA

    Phonophobia, n (%)

NA

15 (53.57%)

NA

    Age at onset, years

NA

17.00 (13.00, 39.55)

NA

    Disease duration, years

NA

3.50 (1.00, 14.00)

NA

    VAS score (0–10)

NA

4.00 (3.00, 7.00)

NA

    HIT-6 score (36–78) a

NA

62.64 ± 10.94

NA

    PHQ-9 score (0–27) b

NA

10.04 ± 6.89

NA

    GAD-7 score (0–21) a

NA

6.80 ± 5.26

NA

    PSQI score (0–21) a

NA

10.20 ± 5.03

NA

  1. Data are presented as mean ± standard deviation or as median [interquartile range, IQR]
  2. NDPH New daily persistent headache; NA Not applicable; BMI Body mass index; VAS Visual analogue scale; HIT-6 Headache Impact Test-6; PHQ-9 Patient Health Questionnaire-9; GAD-7 Generalized Anxiety Disorder-7; PSQI Pittsburgh Sleep Quality Index
  3. aScales data were obtained from twenty-five patients with NDPH
  4. bScales data were obtained from twenty-six patients with NDPH