Brain regions | Side | Disease duration r (p-value) | VAS score r (p-value) | HIT-6 score r (p-value) | PHQ-9 score r (p-value) | GAD-7 score r (p-value) | PSQI score r (p-value) | MoCA score r (p-value) |
---|---|---|---|---|---|---|---|---|
Seed: right lingual gyrus; FC: patients < HCs | ||||||||
 Cluster 1 | ||||||||
  Calcarine | R | 0.070 (0.719) | -0.079 (0.686) | 0.036 (0.086) | -0.195 (0.339) | 0.013 (0.948) | 0.256 (0.217) | -0.074 (0.772) |
  Fusiform gyrus | R | -0.032 (0.870) | 0.048 (0.804) | 0.120 (0.569) | -0.244 (0.230) | 0.114 (0.579) | -0.017 (0.936) | -0.071 (0.780) |
  Calcarine | L | -0.118 (0.544) | -0.046 (0.814) | -0.137 (0.514) | -0.269 (0.183) | 0.014 (0.947) | 0.056 (0.792) | 0.137 (0.587) |
Seed: left superior occipital gyrus; FC: patients < HCs | ||||||||
 Cluster 1 | ||||||||
  Lingual gyrus | R | 0.205 (0.287) | 0.033 (0.865) | 0.217 (0.297) | -0.241 (0.236) | 0.065 (0.763) | 0.185 (0.377) | -0.195 (0.435) |
  Fusiform gyrus | R | 0.039 (0.839) | 0.006 (0.977) | 0.030 (0.886) | -0.228 (0.263) | 0.120 (0.559) | 0.015 (0.945) | 0.030 (0.905) |
Seed: right middle occipital gyrus; FC: patients < HCs | ||||||||
 Cluster 1 | ||||||||
  Lingual gyrus | R | 0.234 (0.221) | 0.116 (0.549) | 0.242 (0.243) | -0.277 (0.270) | 0.077 (0.710) | 0.021 (0.922) | -0.137 (0.586) |
  Lingual gyrus | L | 0.198 (0.303) | 0.070 (0.718) | 0.276 (0.181) | -0.265 (0.190) | 0.081 (0.693) | 0.101 (0.630) | -0.069 (0.786) |
  Calcarine | R | 0.185 (0.335) | 0.051 (0.792) | 0.268 (0.194) | -0.322 (0.109) | 0.022 (0.915) | -0.056 (0.790) | -0.008 (0.975) |
  Fusiform gyrus | R | 0.049 (0.803) | 0.102 (0.598) | 0.057 (0.787) | -0.188 (0.358) | 0.160 (0.435) | 0.037 (0.862) | 0.319 (0.397) |
Seed: left inferior occipital gyrus; FC: patients > HCs | ||||||||
 Cluster 1 | ||||||||
  Superior frontal gyrus, medial | R | 0.023 (0.907) | 0.192 (0.319) | 0.158 (0.452) | -0.019 (0.925) | 0.236 (0.247) | 0.093 (0.660) | 0.104 (0.681) |
Seed: left inferior occipital gyrus; FC: patients < HCs | ||||||||
 Cluster 1 | ||||||||
  Lingual gyrus | L | -0.038 (0.845) | -0.010 (0.961) | 0.254 (0.220) | -0.257 (0.204) | -0.029 (0.889) | -0.025 (0.907) | -0.209 (0.406) |
  Fusiform gyrus | L | -0.054 (0.779) | 0.143 (0.461) | 0.112 (0.594) | -0.184 (0.369) | 0.126 (0.540) | 0.068 (0.746) | 0.032 (0.898) |
  Inferior occipital gyrus | L | 0.017 (0.932) | 0.033 (0.864) | -0.009 (0.966) | 0.258 (0.203) | 0.099 (0.630) | -0.009 (0.967) | -0.084 (0.739) |
 Cluster 2 | ||||||||
  Middle occipital gyrus | R | 0.312 (0.100) | 0.054 (0.780) | 0.225 (0.279) | -0.175 (0.392) | 0.131 (0.525) | 0.160 (0.444) | -0.144 (0.568) |
  Lingual gyrus | R | -0.017 (0.931) | 0.065 (0.738) | 0.207 (0.321) | -0.280 (0.166) | -0.099 (0.631) | 0.028 (0.895) | 0.106 (0.675) |
  Inferior occipital gyrus | R | 0.104 (0.593) | 0.114 (0.555) | -0.111 (0.597) | -0.288 (0.154) | 0.028 (0.892) | -0.034 (0.873) | -0.326 (0.186) |
Seed: right inferior occipital gyrus; FC: patients < HCs | ||||||||
 Cluster 1 | ||||||||
  Lingual gyrus | L | 0.046 (0.813) | 0.010 (0.958) | 0.297 (0.150) | 0.246 (0.226) | 0.017 (0.936) | -0.124 (0.555) | 0.053 (0.833) |
  Fusiform gyrus | L | 0.050 (0.797) | 0.003 (0.986) | 0.125 (0.552) | 0.254 (0.210) | 0.049 (0.812) | 0.151 (0.471) | 0.124 (0.624) |
  Inferior occipital gyrus | L | 0.069 (0.721) | 0.077 (0.691) | -0.051 (0.807) | 0.265 (0.191) | 0.027 (0.894) | 0.027 (0.897) | 0.184 (0.464) |
 Cluster 2 | ||||||||
  Lingual gyrus | R | 0.058 (0.765) | 0.067 (0.730) | 0.231 (0.266) | 0.265 (0.191) | 0.059 (0.773) | 0.111 (0.596) | -0.078 (0.759) |
  Fusiform gyrus | R | -0.093 (0.633) | 0.130 (0.500) | 0.142 (0.499) | -0.186 (0.364) | 0.080 (0.698) | 0.031 (0.884) | 0.126 (0.618) |
Seed: right fusiform gyrus; FC: patients < HCs | ||||||||
 Cluster 1 | ||||||||
  Lingual gyrus | R | 0.092 (0.634) | 0.106 (0.586) | 0.234 (0.261) | -0.190 (0.354) | 0.069 (0.737) | 0.126 (0.548) | -0.105 (0.679) |
  Lingual gyrus | L | 0.088 (0.648) | 0.013 (0.947) | 0.204 (0.328) | -0.219 (0.283) | 0.084 (0.684) | 0.083 (0.695) | -0.018 (0.943) |
  Inferior occipital gyrus | R | 0.054 (0.782) | 0.153 (0.429) | 0.115 (0.584) | -0.204 (0.317) | 0.014 (0.944) | -0.012 (0.956) | -0.315 (0.203) |
  Calcarine | R | 0.077 (0.690) | -0.004 (0.982) | 0.283 (0.171) | 0.189 (0.354) | 0.017 (0.934) | 0.134 (0.524) | -0.102 (0.687) |
 Cluster 2 | ||||||||
  Cuneus | R | 0.245 (0.201) | -0.002 (0.992) | 0.286 (0.165) | -0.245 (0.227) | 0.047 (0.819) | 0.005 (0.981) | 0.034 (0.894) |
  Superior occipital gyrus | R | 0.156 (0.420) | -0.166 (0.510) | 0.213 (0.306) | -0.15 (0.465) | 0.075 (0.718) | 0.144 (0.492) | -0.166 (0.510) |
Seed: left postcentral gyrus; FC: patients < HCs | ||||||||
 Cluster 1 | ||||||||
  Postcentral gyrus | R | 0.176 (0.361) | 0.286 (0.132) | 0.042 (0.842) | -0.134 (0.514) | 0.211 (0.300) | -0.009 (0.967) | 0.074 (0.771) |
  Precentral gyrus | R | -0.010 (0.959) | 0.232 (0.225) | 0.051 (0.810) | -0.154 (0.453) | 0.081 (0.695) | -0.031 (0.885) | 0.090 (0.722) |
Seed: right postcentral gyrus; FC: patients < HCs | ||||||||
 Cluster 1 | ||||||||
  Postcentral gyrus | L | 0.113 (0.559) | 0.178 (0.355) | 0.002 (0.991) | 0.226 (0.267) | 0.141 (0.492) | -0.069 (0.742) | -0.078 (0.757) |
  Precentral gyrus | L | -0.011 (0.956) | 0.176 (0.362) | 0.021 (0.920) | -0.213 (0.296) | -0.081 (0.695) | -0.113 (0.692) | 0.189 (0.452) |
 Cluster 2 | ||||||||
  Precentral gyrus | R | -0.092 (0.635) | 0.225 (0.231) | -0.072 (0.731) | -0.171 (0.404) | 0.016 (0.939) | 0.201 (0.425) | 0.229 (0.231) |
Seed: right thalamus; FC: patients > HCs | ||||||||
 Cluster 1 | ||||||||
  Cuneus | L | -0.173 (0.370) | -0.062 (0.750) | 0.208 (0.319) | 0.237 (0.243) | 0.118 (0.566) | -0.043 (0.839) | -0.015 (0.952) |
  Cuneus | R | -0.136 (0.483) | -0.071 (0.713) | 0.166 (0.427) | 0.232 (0.255) | 0.075 (0.716) | -0.055 (0.794) | -0.087 (0.731) |
  Calcarine | L | 0.183 (0.343) | 0.062 (0.751) | 0.195 (0.349) | -0.107 (0.602) | 0.157 (0.445) | 0.008 (0.971) | 0.023 (0.928) |
  Superior occipital gyrus | R | -0.018 (0.924) | 0.121 (0.531) | 0.330 (0.107) | 0.176 (0.389) | 0.122 (0.554) | 0.014 (0.949) | -0.231 (0.356) |
Seed: right superior temporal gyrus; FC: patients < HCs | ||||||||
 Cluster 1 | ||||||||
  Postcentral gyrus | R | -0.074 (0.704) | 0.289 (0.129) | 0.252 (0.223) | 0.018 (0.932) | 0.183 (0.370) | 0.042 (0.842) | 0.339 (0.169) |
  Rolandic operculum | R | 0.042 (0.828) | 0.371 (0.048) | 0.350 (0.087) | -0.083 (0.688) | 0.088 (0.688) | 0.220 (0.290) | 0.220 (0.380) |