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Table 2 Brain regions with aberrant functional connectivity

From: Mapping the aberrant brain functional connectivity in new daily persistent headache: a resting-state functional magnetic resonance imaging study

Brain regions

Side

MNI coordinates

Peak t-valve

Cluster size

Cluster level

PFWE corr

x

y

z

Seed: right lingual gyrus; FC: patients < HCs

 Cluster 1

 

12

-63

6

3.23

321

< 0.001

  Calcarine

R

      

  Fusiform gyrus

R

      

  Calcarine

L

      

Seed: left superior occipital gyrus; FC: patients < HCs

 Cluster 1

 

18

-81

0

4.51

118

0.027

  Lingual gyrus

R

      

  Fusiform gyrus

R

      

Seed: right middle occipital gyrus; FC: patients < HCs

 Cluster 1

 

21

-45

3

4.89

481

< 0.001

  Lingual gyrus

R

      

  Lingual gyrus

L

      

  Calcarine

R

      

  Fusiform gyrus

R

      

Seed: left inferior occipital gyrus; FC: patients > HCs

 Cluster 1

 

3

45

51

4.47

129

0.021

  Superior frontal gyrus, medial

R

      

Seed: left inferior occipital gyrus; FC: patients < HCs

 Cluster 1

 

-30

-78

6

5.12

234

0.001

  Lingual gyrus

L

      

  Fusiform gyrus

L

      

  Inferior occipital gyrus

L

      

 Cluster 2

 

39

-84

0

4.31

182

0.005

  Middle occipital gyrus

R

      

  Lingual gyrus

R

      

  Inferior occipital gyrus

R

      

Seed: right inferior occipital gyrus; FC: patients < HCs

 Cluster 1

 

-12

-78

12

5.07

298

< 0.001

  Lingual gyrus

L

      

  Fusiform gyrus

L

      

  Inferior occipital gyrus

L

      

 Cluster 2

 

21

-45

3

4.39

225

0.002

  Lingual gyrus

R

      

  Fusiform gyrus

R

      

Seed: right fusiform gyrus; FC: patients < HCs

 Cluster 1

 

27

-66

-9

5.36

786

< 0.001

  Lingual gyrus

R

      

  Lingual gyrus

L

      

 Inferior occipital gyrus

R

      

  Calcarine

R

      

 Cluster 2

 

15

-81

39

5.05

160

0.007

  Cuneus

R

      

  Superior occipital gyrus

R

      

Seed: left postcentral gyrus; FC: patients < HCs

 Cluster 1

 

45

-18

33

4.28

298

< 0.001

  Postcentral gyrus

R

      

  Precentral gyrus

R

      

Seed: right postcentral gyrus; FC: patients < HCs

 Cluster 1

 

-42

-12

48

4.69

494

< 0.001

  Postcentral gyrus

L

      

  Precentral gyrus

L

      

 Cluster 2

 

30

-27

60

4.56

166

0.008

  Precentral gyrus

R

      

Seed: right thalamus; FC: patients > HCs

 Cluster 1

 

-6

-90

18

4.64

217

0.004

  Cuneus

L

      

 Cuneus

R

      

  Calcarine

L

      

  Superior occipital gyrus

R

      

Seed: right superior temporal gyrus; FC: patients < HCs

 Cluster 1

 

42

0

18

4.59

108

0.035

  Postcentral gyrus

R

      

  Rolandic operculum

R

      
  1. FC functional connectivity, HCs healthy controls, MNI Montreal Neurological Institute, L left, R right, FWE corr family wise error correction. Brain region localizations were performed using an automatic anatomical labeling atlas, and the number of voxels of the anatomical regions in which the cluster extends to were reported