From: Periaqueductal gray matter echogenicity as a marker of migraine chronification: a case control study
Controls (n = 50) | Migraine patients (n = 65) | CM (n = 39) | EM (n = 26) | Controls vs migraine patients | Controls vs CM | Controls vs EM | CM vs EM | |
---|---|---|---|---|---|---|---|---|
Bed-side analysis | ||||||||
PAG area | 0.12 [0.09;0.15] | 0.13 [0.11;0.17] | 0.15 [0.12;0.22] | 0.11 [0.10;0.14] | 0,043* | 0,004* | 0,895 | 0.017 |
Right RN | 0.06 [0.05;0.08] | 0.05 [0.04;0.07] | 0.05 [0.04;0.07] | 0.06 [0.05;0.07] | 0,281 | 0,336 | 0,369 | 0.940 |
Left RN | 0.07 [0.05;0.09] | 0.07 [0.05;0.08] | 0.07 [0.05;0.09] | 0.06 [0.05;0.08] | 0,868 | 0,962 | 0,782 | 0.763 |
Right SN area | 0.09 [0.07;0.12] | 0.10 [0.08;0.13] | 0.11 [0.08;0.14] | 0.10 [0.07;0.12] | 0,082 | 0,013* | 0,935 | 0.127 |
Left SN area | 0.11 [0.08;0.13] | 0.11 [0.09;0.13] | 0.11 [0.09;0.14] | 0.10 [0.08;0.13] | 0,793 | 0,478 | 0,697 | 0.308 |
IIIv size | 0.33 [0.27;0.45] | 0.29 [0.21;0.44] | 0.29 [0.21;0.46] | 0.30 [0.25;0.38] | 0,092 | 0,13 | 0,205 | 0.914 |
Right horn LV | 1.40 [1.26;1.55] | 1.45 [1.32;1.60] | 1.54 [1.40;1.60] | 1.39 [1.25;1.47] | 0,367 | 0,06 | 0,535 | 0.026* |
Left horn LV | 1.50 [1.32;1.68] | 1.49 [1.35;1.67] | 1.49 [1.31;1.60] | 1.54 [1.35;1.68] | 0,771 | 0,868 | 0,462 | 0.352 |
Horos analysis | ||||||||
PAG area | 0.13 [0.12;0.18] | 0.16 [0.13;0.20] | 0.16 [0.13;0.20] | 0.17 [0.12;0.20] | 0,038* | 0,04* | 0,191 | 0.650 |
PAG echogenicity (intensity) | 109.56 [83.30;122.64] | 93.84 [71.34;117.26] | 90.57 [70.87;117.26] | 101.70 [76.44;115.17] | 0,07 | 0,035* | 0,457 | 0.221 |
PAG echogenicity (CV) | 25.40 [20.08;31.84] | 29.26 [23.69;35.02] | 32.24 [25.74;35.83] | 25.84 [21.78;30.95] | 0,12 | 0,009* | 0,688 | 0.003* |
Right SN area | 0.10 [0.08;0.14] | 0.12 [0.10;0.15] | 0.13 [0.09;0.14] | 0.12 [0.10;0.15] | 0,006* | 0,09* | 0,003* | 0.260 |
Rigth SN echogenicity (intensity) | 82.87 [68.57;95.34] | 79.76 [63.52;100.93] | 79.76 [59.48;99.03] | 80.80 [67.74;101.18] | 0,96 | 0,769 | 0,8 | 0.743 |
Rigth SN echogenicity (CV) | 27.08 [20.92;33.90] | 28.13 [22.45;37.52] | 29.27 [20.37;40.22] | 27.48 [23.30;34.00] | 0,545 | 0,624 | 0,608 | 0,940 |
Right RN area | 0.07 [0.07;0.08] | 0.08 [0.07;0.09] | 0.08 [0.07;0.09] | 0.08 [0.07;0.10] | 0,954 | 0,96 | 0,838 | 0.612 |
Rigth RN echogenicity (intensity) | 85.54 [67.46;104.89] | 69.61 [53.52;97.05] | 75.59 [53.52;86.33] | 61.56 [56.12;100.41] | 0,062 | 0,077 | 0,15 | 1.000 |
Rigth RN echogenicity (CV) | 23.85 [20.04;29.51] | 28,79 [20.59;31.83] | 28.92 [22.10;32.81] | 28.30 [26.43;30.69] | 0,135 | 0,193 | 0,193 | 0.780 |
Left SN area | 0.10 [0.08;0.12] | 0.11 [0.09;0.16] | 0.11 [0.09;0.16] | 0.12 [0.09;0.16] | 0,01* | 0,027* | 0,033* | 0.632 |
Left SN echogenicity (intensity) | 82.17 [55.90;102.12] | 78.06 [62.68;95.60] | 74.35 [64.13;94.45] | 80.49 [61.23;106.43] | 0,972 | 0,827 | 0,709 | 0.500 |
Left SN echogenicity (CV) | 26.39 [20.16;29.87] | 28.43 [21.77;35.20] | 28.43 [23.07;32.66] | 27.07 [21.41;36.30] | 0,163 | 0,179 | 0,348 | 0.848 |
Left RN area | 0.08 [0.05;0.09] | 0.07 [0.05;0.10] | 0.07 [0.06;0.08] | 0.08 [0.05;0.11] | 0,796 | 0,837 | 0,377 | 0.675 |
Left RN echogenicity (intensity) | 89.34 [73.36;108.69] | 8.,45 [59.84;96.68] | 85.47 [68.49;96.60] | 76.00 [58.66;106.75] | 0,235 | 0,268 | 0,377 | 0.884 |
Left RN echogenicity (CV) | 25.18 [22.07;37.25] | 29.86 [22.80;55.92] | 35.51 [24.82;64.38] | 23.97 [21.06;31.34] | 0,383 | 0,124 | 0,679 | 0.051 |