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Table 1 Demographic and clinical characteristics of patients with migraine and controls

From: Periaqueductal gray matter echogenicity as a marker of migraine chronification: a case control study

 

Controls (n = 50)

Migraine patients (n = 65)

CM (n = 39)

EM (n = 26)

p value (C vs M)

p value (CM vs EM)

Age (years)

43.50

[28.00;65.00]

45.00

[38.00;53.00]

45.00

[38.00;53.00]

45.00

[38.00;54.00]

0.954

0.981

Sex, female (n,%)

34 (68%)

47 (72.3%)

27 (69.23%)

20 (76.92%)

0.682

0.579

Disease duration (years)

-

30.00

[20.00;40.00]

29.00

[19.00;40.00]

30.00

[22.00;40.00]

-

0.384

Duration of CM (months)

-

-

60.00

[40.00;120.00]

 

-

NA

Days of migraine per month

-

14.00

[10.00;19.00]

18.00

[14.00;27.00]

9.00

[2.00;12.00]

-

 < 0.001

Days of headache per month

-

20.00

[12.00;30.00]

28.00

[24.00;30.00]

9.50

[3.00;12.00]

-

 < 0.001

NSAIDs overuse (n,%)

-

-

11 (28.21%)

1 (3.85%)

-

0.02

Triptans overuse (n,%)

-

-

12 (30.77%)

7 (26.92%)

-

0.787

MIDAS, total score

-

60.00

[20.00;96.00]

84.00

[56.00;122.00]

21.00

[3.50;36.50]

-

 < 0.001

HIT-6

 

67.00

[62.00;70.00]

68.00

[65.00;70.00]

64.00

[55.50;67.00]

-

0.004

MSQV2.19

 

42.85

[30.00;65.58]

34.29

[22.85;51.43]

63.58

[46.43;88.58]

-

 < 0001

HADS Anxiety, score

-

9.00

[6.00;14.00]

11.00

[7.00;16.00]

7.50

[4.00;10.00]

-

0.002

HADS Depression, score

 

6.00

[4.00;10.00]

9.00

[5.00;12.00]

4.00

[3.00;8.00]

-

0.001

  1. C Controls, M Migraine patients, CM Chronic migraine, EM Episodic migraine, NSAIDs Nonsteroidal anti-inflammatory drugs, MIDAS Migraine Disability Assessment Scale, HIT-6 Headache Impact Test, MSQV2.19 Version 2 of the Migraine-Specific Quality-of-Life Questionnaire, HADS Hospital Anxiety and Depression Scale