Fig. 3

Comparison of relative concentration of total brain metabolites in different parts. Compared with RTNC, * denotes P < 0.05, ** denotes P < 0.01; Compared with the model group, # indicates P < 0.05, and ## indicates P < 0.01. There were no significant differences in rLac, rAla, rAce, rGABA and rGly between LTNC and RTNC; There were significant differences in rLac, rAce, rGABA and rGly between PAG and RTNC which showed the rLac and rGly of PAG were lower than those of RTNC while the rAce and rGABA of PAG were higher than those of RTNC. The rLac, rAla and rGABA were statistically different among the groups (PAG, LTNC and RTNC), indicating the rAla and rGABA in the model group were lower than those in the control group and the blank group, when the rLac in the model group were higher than those in the control group and the blank group