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Table 2 Treatments that can modify levels of prolactin

From: Prolactin and oxytocin: potential targets for migraine treatment

Treatment

Mechanism of action

Prolactin levels

Bromocriptine

Dopamine direct-acting receptor agonist

↓ Decrease [22, 114]

Chlorpromazine

Dopamine receptor antagonist

↑ Increase [22, 152]

Methysergide

Competitive blocker of serotonin receptors

↑ Increase – transient effect [22, 153, 154]

Fenfluramine

5-HT2B receptor agonist

↑ Increase [22, 155]