The Journal of Headache and Pain

Table 1 Influence on prolactin levels of approved treatments for migraine (acute and prophylaxis)

From: Prolactin and oxytocin: potential targets for migraine treatment

	Treatment	Prolactin levels
Acute	Acetaminophen	↓ Decrease [134]
	Aspirin	No evidence [134]
	Triptans (sumatriptan)	↓ Decrease [135, 136]
Prophylactic	Propranolol	↓ Decrease – chronic use [137, 138]
	Flunarizine	↑ Increase – transient effect [139, 140]
	Amitriptyline	No effect [141,142,143]
	Topiramate	No evidence [144,145,146]
	Valproate	↑ Increase [146,147,148]
	Botulinum toxin	No evidence [149, 150]

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ISSN: 1129-2377

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