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Table 1 The results of sensitivity analysis

From: Causal relationships between migraine and microstructural white matter: a Mendelian randomization study

Exposure

Outcome

MR-egger regression

MR-PRESSO Global test

Cochran’s Q-test

The MO in left inferior fronto-occipital fasciculus (IDP 1587)

Migraine

NA

NA

NA

The OD in right posterior thalamic radiation (IDP 2005)

Migraine

Intercept = 0.04

p = 0.27

RSS = 10.96

p = 0.34

Q-value = 8.63

p = 0.28

Migraine

The MO in right uncinate fasciculus (IDP 1571)

Intercept = − 0.01

p = 0.47

RSS = 105.74

p < 1.00 × 10− 3

Q-value = 99.38

p = 1.29 × 10− 7

Migraine

The OD in left superior cerebellar peduncle (IDP 1990)

Intercept = − 0.01

p = 0.88

RSS = 49.10

p = 0.14

Q-value = 46.69

p = 0.13

  1. Abbreviations: IDPs imaging-derived phenotypes, MO mode of anisotropy, OD orientation dispersion index, RSS residual sum of squares