Fig. 4

Correlations between the clinical parameters and brain regions in which the GMV changed in patients with CTN. (A) The GMV of TPOsup_L was negatively correlated with self-rating anxiety scale (P = 0.005, r = –0.341), (B) The GMV of TPOsup_R was positively correlated with disease duration (years) (P = 0.030, r = 0.245) and negatively correlated with the CSA of compression point (P = 0.048, r = –0.224) and symptoms of TN QOLS (P = 0.002, r = –0.336). (C) The GMV of precentral_R was negatively correlated with the ipsilatreal TGNcV (P = 0.013, r = –0.278), CSA of the compression point (P = 0.041, r = –0.231), and VAS (P < 0.025, r = –0.252). GMV, gray matter volume; CTN, classical trigeminal neuralgia; CSA, cross-sectional area; TN QOLS, quality-of-life score of patients with trigeminal neuralgia; TGNcV, volume of trigeminal nerve cisternal segment