Table 1 The results of comparing different groups. The left column lists the factors compared. The numbers in the right columns are p-values. P < 0.05 is was defined as statistically significant. The letters following P values (highlighted in red) indicate the group names with existing differences (x/x). Group J1: onset before menarche; group J2: onset after menarche but before childbirth; group J3: onset after childbirth. J1-1 and J2-1: patients reported an aggravation after childbirth in groups J1 and J2. J1-2 and J2-2: patients reported unchanged after childbirth in groups J1 and J2.. Abbreviation: AS = accompanied symptom, Y/N = yes/no, PS = premonitory symptoms, BMI = Body Mass Index

1

Menstruation relationship(Y/N)

0.421

0.282

0.966

0.031 L

2

Family history

0.001 A, B/C

0.288

0.000 G, H/I

0.162

3

Headache side

0.560

0.579

0.322

0.134

4

NRS score

0.455

0.469

0.023 G/I

0.871

NRS score degree

0.655

0.224

0.113

0.191

5

Pulsating pain (Y/N)

0.02 B/C

0.119

0.008 H/I

0.302

6

Headache local (front)

0.000 B/C

0.039 E/F

0.008 H/I

0.145

(back)

0.275

0.230

0.763

0.708

7

Aggravation after activity

0.005 A,B/C

0.122

0.095 G/I

0.754

8

nausea

0.686

0.870

0.158

0.871

vomit

0.154

0.765

0.048 H/I

0.471

photophobia

0.001 A/C

0.026 D/F

0.007 G/H,I

0.669

phonophobia

0.001 A/B,C

0.034 D/E,F

0.042 G/I

0.950

9

With PS

0.092 A/C

0.836

0.001 G/H,I

0.260

10

Number of PS

0.034 A/B; A/C

0.884

0.000 G/H; G/I

0.112

11

Trigger (Y/N)

0.01 A,B/C

0.638

0.002 G,H/I

0.008 J

12

Number of triggers

0.000 A/B/C

0.05 D/F

0.000 G/H/I

0.596

13

Typical score

0.000 A,B/C

0.007 D,E/F

0.000 G,H/I

0.966

Typical degree

0.000 A/B/C

0.037 D/F

0.000 G/H/I

0.286

14

Headache frequency/month

0.019 B/C

0.000 E/F

0.801

0.000 J

15

Chronic daily headache

0.028 B/C

0.000 D, E/F

0.771

0.000 J

16

Medicine overused headache

0.031 A, B/C

0.000 D, E/F

0.374

0.000 J

17

Educational level

0.000 A,B/C

0.000 D,E/F

0.012 G,H/I

0.640

18

BMI

0.019 A/C; B/C

0.111

0.258

0.278

19

Sleep disorder score

0.465

0.199

0.977

0.397

SD of falling asleep

0.01 B/C

0.121

0.217

0.786

dreaminess

0.249

0.475

0.391

0.352

early waking

0.021 A/B,C; B/C

0.002 D/E,F; E/F

0.974

0.815

daytime sleepiness

0.991

0.975

0.560

0.849

20

PHQ-9 score

0.000 A/C; B/C

0.000 D/F; E/F

0.02 G/I; H/I

0.404

21

GAD-7 score

0.487

0.262

0.945

0.445

22

Smoking status

0.306

0.723

0.311

0.824

23

Consumption of alcohol

0.306

0.723

0.311

0.824

24

Consumption of tea (Y/N)

0.502

0.634

0.713

0.640

scale

0.493

0.611

0.720

0.605

25

Consumption of coffee (Y/N)

0.000 A,B/C

0.000 E/F

0.009 H/I

0.706

Scale

0.000 A,B/C

0.000 E/F

0.009 H/I

0.753

26

Exercise status

0.227

0.538

0.348

0.435