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Table 5 Review the literature of FTN with CMT

From: MARS1 mutations linked to familial trigeminal neuralgia via the integrated stress response

Year

Reference

CMT Affected Members

Type of CMT

Sex(M/F) for CMT

TN Affected Members

Sex(M/F) for TN

Age of TN onset (min–max)

Other Cranial Nerve Involvement

Treatment

Probably related genes

2000

Marcus de Matas et al. [37]

2

NA

2/0

2

2/0

24–41

 NA

 NA

NA

2004

Todd R. Aho et al. [38]

3

CMT1A

2/1

3

2/1

NA

 NA

 NA

PMP22

Robert J. Coffey et al.

8

NA

3/5

4

1/3

39-?

 NA

 NA

NA

1977

Cruse, RP et al. [39]

13

CMT1

6/7

6

More than 4 females

 NA

Hearing loss Demyelinating with seventh and eighth nerve

Carb Decompression

NA

2000

L.Tacconi et al. [40]

2

NA

2/0

2

2/0

19–24

 NA

Carb Decompression

NA

1981

D. Testa et al. [41]

8

CMT1

6/2

3

2/1

35–46

Motor conduction times of the facial nerves were bilaterally prolonged

 NA

NA

1978

S. K. Mongia et al. [42]

17

NA

9/8

4

NA

NA

 NA

Nerve blocks

Medical

NA

2019

Jean Loup Méreaux et al. [6]

8

CMT1B

3/5

4

0/4

30–51

Hearing loss

Carb, gaba, phenytoin, amitriptyline, clonazepam

Thermocoagulation

MPZ

2019

James B. Caress et al. [16]

27

CMT1B

11/16

5

0/5

 NA

Hemifacial spasm

 NA

MPZ

  1. Carb Carbamazepine, Gaba Gabapentine, NA Not available