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Table 1 The Demographic data and baseline characteristics of probands

From: MARS1 mutations linked to familial trigeminal neuralgia via the integrated stress response

Variable

Patient

Sex

Age(y)

Age of onset(y)

Symptomatic site

Therapeutics

BNI

VAS

MRI feature

Surgery feature

BNI (at least 6 m after surgery)

VAS (at least 6 m after surgery)

Complications

Follow up(mo)

Family 1

II-1

F

59

42

Left, V2 and V3

Carba

III

7

The left superior cerebellar artery is closely related to the trigeminal nerve

NA

NA

NA

NA

12

II-2

M

53

44

Left, V2 and V3

Carba, Gaba, Oxcarba

IV

8

The left superior cerebellar artery is closely related to the trigeminal nerve

The superior cerebellar artery compresses the trigeminal nerve root

II

4

Infection, dizzy

12

II-3

M

51

32

Left, V2 and V3

Carba

V

9

The left superior cerebellar artery is closely related to the trigeminal nerve

The superior cerebellar artery compresses the trigeminal nerve root

I

2

Infection

18

Family2

II-1

F

53

36

Left (dominant) and right, V2(left) and V2(Right)

Carba

IV

7

Bilateral trigeminal nerves are close to cerebellar artery

Severe compression at the root entry zone of the trigeminal nerve by the superior cerebellar artery

II

5

Dizzy

17

II-2

F

50

37

Right, V2

Carba

V

9

Bilateral trigeminal nerves are close to cerebellar artery

The superior cerebellar artery compresses the trigeminal nerve root

I

2

NA

9

Family3

I-1

F

71

70

Right, V3

Carba

IV

8

The right superior cerebellar artery is closely related to the trigeminal nerve

NA

I

1

NA

6

II-2

F

44

34

Left, V3

Carba

III

6

The superior cerebella artery located on the inside of the trigeminal root

NA

NA

NA

NA

6

  1. V1 Ophthalmic, V2 Maxillary, V3 Mandibular afferent fibre, BNI Barrow Neurological Institute, VAS Visual Analogue Scale, Carb Carbamazepine, Gaba Gabapentine, Oxcarb Oxcarbazepine, NA Not available, m months