Table 3 Association between migraine medication use and spontaneous abortion (n = 7890)^a

 Non-migraineur

1199

6207

Ref

Ref

 Migraineur, no medication use

168

893

0.97 (0.83–1.14)

0.96 (0.82–1.13)

 Migraineur, medication use

145

662

1.15 (0.97–1.37)

1.14 (0.96–1.36)

Frequency of use

 Less than daily

121

572

1.10 (0.91–1.32)

1.08 (0.90–1.32)

 Daily

 14

 55

 1.38 (0.81–2.33)

 1.38 (0.81–2.35)

Type

 Over-the-counter treatment

 102

 456

 1.17 (0.94–1.45)

 1.16 (0.93–1.44)

 Prescription treatment

32

165

1.04 (0.71–1.53)

1.04 (0.71–1.53)

 Prescription prophylaxis

11

41

1.41 (0.70–2.83)

1.43 (0.72–2.84)

Ingredients

 Analgesic(s), and caffeine

 31

119 

 1.38 (0.97–1.98)

 1.42 (0.99–2.04

 Triptans

19

77

1.30 (0.83–2.05)

1.30 (0.83–2.07)