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Fig. 2 | The Journal of Headache and Pain

Fig. 2

From: Longitudinal changes in functional connectivity and pain-induced brain activations in patients with migraine: a functional MRI study pre- and post- treatment with Erenumab

Fig. 2

Main effect of painful heat applied to the left forearm at baseline (i.e. pre-treatment). A) immediate BOLD response to painful stimulation (measured starting with the MRI frame during which the painful heat stimulus began and ending 12.5 s later). B) delayed BOLD response to painful stimulation (measured starting 12.5 s after onset of painful heat stimulus and ending 12.5 s later). Hotter colors represent stronger activation

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