Fig. 2From: Longitudinal changes in functional connectivity and pain-induced brain activations in patients with migraine: a functional MRI study pre- and post- treatment with ErenumabMain effect of painful heat applied to the left forearm at baseline (i.e. pre-treatment). A) immediate BOLD response to painful stimulation (measured starting with the MRI frame during which the painful heat stimulus began and ending 12.5 s later). B) delayed BOLD response to painful stimulation (measured starting 12.5 s after onset of painful heat stimulus and ending 12.5 s later). Hotter colors represent stronger activationBack to article page