Fig. 1

Temporal summation of pain in burning mouth syndrome (BMS) patients and control subjects. A Time course of pain perception evoked by repetitive laser painful stimuli applied of the hand in control subjects, and BMS patients. Testing sessions consisted of a series of 15 blocks of 4 thermal test stimuli (Nd:YAP laser stimulator) that were delivered at 0.2 Hz on the back of the non-dominant hand, repeated every 40 s for 10 min. Mean pain ratings (± SEM) are shown from the first to the 15th stimulation. *Linear mixed model: P = 0.012 for group, P < 0.001 for time, P = 0.514 for time × group. B Sum of pain intensity between 1^st-15^th.^. *P value is from two-tailed Student's unpaired t-test