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Table 4 Comorbidities

From: Migraine epidemiology and comorbidities in Southern Israel: a clinical database study in a universal health coverage setting

Variable, n (%)

Migraine patients (n = 26,545)

Non-migraine controls* (n = 53,090)

P

Psychiatric disorders

 Anxiety

956 (3.6%)

1009 (1.9%)

 < 0.001

 Depression

849 (3.2%)

584 (1.1%)

  < 0.001

Cardiovascular risk factors

 Obesity (BMI > 30 kg/m2)

8335 (31.4%)

20,280 (38.2%)

 < 0.001

 Dyslipidemia

7459 (28.1%)

13,538 (25.5%)

 < 0.001

 Essential hypertension

5362 (20.2%)

6318 (11.9%)

 < 0.001

 Diabetes mellitus

2708 (10.2%)

7433 (14.0%)

 < 0.001

 Pre-diabetes

1141 (4.3%)

3026 (5.7%)

 < 0.001

Pain disorders

 Fibromyalgia

1752 (6.6%)

2124 (4.0%)

 < 0.001

 Low back pain

2734 (10.3%)

4778 (9.0%)

 < 0.001

 Disc lesions

1274 (4.8%)

2071 (3.9%)

 < 0.001

Other

 Hypothyroidism

2071 (7.8%)

4300 (8.1%)

0.249

 Vitamin D deficiency

1858 (7.0%)

3769 (7.1%)

0.616

 Asthma

1832 (6.9%)

3238 (6.1%)

0.238

 Fatty liver

1566 (5.9%)

2973 (5.6%)

0.223

 Vitamin B12 deficiency

1646 (6.2%)

3292 (6.2%)

0.912

 Osteoporosis

1566 (5.9%)

3026 (5.7%)

0.430

 Iron deficiency anemia

903 (3.4%)

2283 (4.3%)

 < 0.001

 Annual mortality (2018)

70 (0.3%)

186 (0.4%)

0.717

  1. BMI body mass index
  2. *The non-migraine control group is matched to the migraine group based on gender, mean age (± 5 years), and primary clinic
  3. Chi-square test for categorical variables/t test for normally distributed variables