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Table 4 Relative frequency of individual premonitory symptoms in clinic-based studies

From: Premonitory symptoms in migraine: a systematic review and meta-analysis of observational studies reporting prevalence or relative frequency

Premonitory symptom

Number of studies

Total number of participants

Pooled relative frequency

% (95% CI)

I2

% (95% CI)

Fatigue

4 [22, 24, 26, 30]

1470

49% (30–68)

80.8% (49.5–92.7)

Neck stiffness

3 [19, 24, 26]

445

46% (20–75)

80.2% (37.7–93.7)

Mood change

3 [26, 30, 31]

1623

37% (10–76)

88.6% (68.7–95.9)

Concentration difficulties

3 [19, 22, 24]

530

30% (25–36)

16.5% (0.0–91.3)

Nausea

4 [22,23,24, 26]

589

29% (13–52)

85.7% (64.8–94.2)

Photophobia

5 [19, 22, 23, 26, 31]

2153

29% (4–80)

97.6% (96.2–98.5)

Phonophobia

5 [19, 22, 23, 26, 31]

898

26% (4–76)

97.5% (96.0–98.5)

Yawning

7 [18, 19, 22, 24, 26, 30, 31]

2492

22% (7–53)

95.5% (92.9–97.2)

Depressive symptoms

5 [18, 19, 22,23,24]

969

19% (7–44)

96.2% (93.4–97.8)

Irritability

3 [19, 22, 24]

530

16% (2–65)

86.4% (60.7–95.3)

Food craving

6 [19, 22, 24, 26, 30, 31]

2153

11% (3–32)

89.3% (79.4–94.5)