Table 5 Clinical characteristics of SUNCT and SUNA from different regions in the world
China 2022 | USA 2021 [14] | UK 2020 [12] | UK 2018 [10] | Portugal 2016 [9] | Australia 2008 [8] | UK 2006 [7] | |||||
|---|---|---|---|---|---|---|---|---|---|---|---|
SUNCT | SUNA | SUNCT and SUNA | SUNCT and SUNA | SUNCT | SUNA | SUNCT | SUNCT | SUNA | SUNCT | SUNA | |
Number of patients | 45 | 31 | 6 | 159 | 65 | 37 | 15 | 17 | 5 | 43 | 9 |
M: F Ratio | 1: 1.14 | 1: 2.10 | 1: 1 | 1: 1.04 | 1: 0.76 | 1: 1.06 | 1: 0.88 | 1: 1.43 | 1: 1.5 | 1: 0.5 | 1: 2 |
Age at diagnosis, mean (SD), y | 41.62 (12.70) | 48.68 (13.80) | NA | 58.7 (15.4) | NA | NA | NA | 46.24 (11.86) | 47.40 (12.72) | NA | NA |
Age at onset, mean (SD), y | 37.22 (14.54) | 42.45 (14.72) | 52 (15) | NA | 46 (13) | 45 (16) | 49.7 (12.5) | 39.94 (14.44) | 46.40 (12.50) | 48 | 44 |
Common sites of pain (%) | Temporal, periorbital, parietal, forehead | Parietal, temporal. occipital, forehead, cheek | V1 and/ or V2 | V1 and/ or V2 | NA | NA | Orbital, supra-orbital, temporal | NA | NA | Eye, retro-orbital, forehead, nose | Temple, retro-orbital, side of head |
Severity (0-10), mean (SD) | 8.13 (1.58) | 8.06 (1.83) | NA | 9.42 (1.42) | NA | NA | NA | NA | NA | NA | NA |
Most cranial autonomic features | Lacrimation, conjunctival injection, rhinorrhoea, nasal congestion | Lacrimation. rhinorrhoea, nasal congestion | Lacrimation, conjunctival injection, rhinorrhoea, facial flushing | NA | Conjunctival injection, lacrimation, nasal blocking or rhinorrhoea, ptosis | Lacrimation, ptosis, nasal blocking or rhinorrhoea, periorbital oedema | Conjunctival injection, lacrimation, ptosis, facial sweating | NA | NA | Conjunctival injection, lacrimation, rhinorrhoea, ptosis | Lacrimation, ptosis, conjunctival injection, rhinorrhoea, nasal blockage |
Common triggers | Cold wind, teeth brushing, face washing | Cold wind, face washing, light touch | Teeth brushing, blowing nose | NA | Touch, chewing or eating, wind, brushing the teeth | Chewing, eating, touch | Touching the face or scalp, chewing, eating | Cool breeze from air conditioning ducts | Touch, chew/eat, wind, wash face | Chew/eat, move | |
Delay to the correct diagnosis, mean (SD), y | 2.5 (0–20.5) | 3.0 (0-20.7) | NA | NA | NA | NA | NA | NA | NA | 6.7 | 7.1 |