The Journal of Headache and Pain

Table 3 Brain regions showing seed-based resting-state FC differences of right CN between CM and EM, HCs

From: Altered functional connectivity of the right caudate nucleus in chronic migraine: a resting-state fMRI study

Brain regions	MNI coordinates			Peak F/t value	Cluster size	Cluster level P_{FWE corr}_.
Brain regions	x	y	z	Peak F/t value	Cluster size	Cluster level P_{FWE corr}_.
Three group comparison
Cluster 1	60	-33	-9	15.78	199	0.003
Temporal_Mid_R
Cluster 2	12	-72	9	11.40	172	0.005
Calcarine_R
Calcarine_L
Cluster 3	42	33	-3	13.75	116	0.026
Frontal_Inf_Orb_R
Frontal_Inf_Tri_R
Cluster 4	3	-3	30	13.10	126	0.019
Cingulum_Mid_R
Cluster 5	24	-66	63	14.12	169	0.006
Parietal_Sup_R
Parietal_Inf_R
CM > HC
Cluster 1	12	-72	9	4.48	432	< 0.001
Calcarine_R
Calcarine_L
Lingual_R
Lingual_L
Cluster 2	27	-69	60	5.19	365	< 0.001
Parietal_Sup_R
Parietal_Inf_R
Precuneus_R
Cluster 3	60	-30	-12	5.43	367	< 0.001
Temporal_Mid_R
Temporal_Inf_R
Temporal_Sup_R
Cluster 4	42	33	-3	4.75	310	0.001
Insula_R
Frontal_Inf_Orb_R
Temporal_Pole_Sup_R
Cluster 5	6	33	3	4.28	138	0.025
Cingulum_Ant_R
Cingulum_Ant_L
CM > EM
Cluster 1	12	-30	36	4.62	182	0.012
Cingulum_Mid_R
Precuneus_R
Precuneus_L
Cingulum_Ant_L
Cluster 2	6	-42	3	4.51	124	0.043
Lingual_R

Note: MNI, Montreal Neurological Institute; L, left; R, right; FWE, family-wise error corrected; CM, chronic migraine; EM, episodic migraine. Brain region localizations were performed using Automatic Anatomical Labeling (AAL) atlas and number of voxels of the anatomical regions in which the cluster extents to are reported. The surviving clusters were assigned thresholds at level p < 0.001 and FWE-corrected to p < 0.05 at the cluster level.

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ISSN: 1129-2377

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