Table 1 Demographic, clinical, and MRI characteristics of patients with episodic migraine and HCs

Demographics

 N

27

30

 Age

34.89 ± 9.070

35.53 ± 12.153

0.820

 Female/male

25/2

30/4

0.467

 Education level

13.70 ± 4.697

14.70 ± 4.473

0.416

 BMI

22.13 ± 3.091

22.31 ± 2.897

0.818

MRI characteristics

 FD (mm)

0.21 ± 0.247

0.13 ± 0.056

0.093

 TIV (cm³)

1399.8681 ± 111.56465

1426.4777 ± 135.39141

0.425

 GM (cm³)

606.4202 ± 45.64292

618.1007 ± 50.83728

0.367

 WM (cm³)

478.5041 ± 44.96136

499.8487 ± 54.89597

0.116

 CSF (cm³)

314.1511 ± 64.42272

307.7677 ± 58.93003

0.698

Migraine characteristics

 Family history

17/27

N/A

 Disease duration (years)

11.11 ± 10.165

N/A

 Aura

7

N/A

 VAS scale

6.37 ± 1.801 (27/27)

N/A

 HIT-6 scale

60.17 ± 6.218 (24/27)

N/A

 HAMA scale

12.43 ± 8.681 (21/27)

4.00 ± 4.520 (29/30)

 < 0.001*

 BDI-II scale

9.53 ± 11.452 (19/27)

4.38 ± 5.054 (21/30)

0.069

 MoCA scale

26.00 ± 3.079 (24/27)

N/A

BFI scale

 neuroticism

32.71 ± 6.663 (24/27)

30.86 ± 7.901 (21/30)

0.339

 extraversion

36.04 ± 5.320 (24/27)

39.90 ± 5.822 (21/30)

0.025*

 openness

36.63 ± 7.756 (24/27)

38.29 ± 5.755 (21/30)

0.425

 agreeableness

43.04 ± 3.873 (24/27)

44.10 ± 3.285 (21/30)

0.334

 conscientiousness

42.46 ± 7.034 (24/27)

44.33 ± 4.004 (21/30)

0.272