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Table 6 Results of the quality of life and cognition tests in the subgroup of patients with CM and normal mood at baseline (n = 14) and after three months of preventive treatment (n = 12)

From: Preventive treatment can reverse cognitive impairment in chronic migraine

 

CM

Pre-treatment

(n = 14)

\(\overline{\mathbf x}\;(\mathbf S\mathbf D)\)  

CM

Post-treatment

(n = 12)

\(\overline{\mathbf x}\;(\mathbf S\mathbf D)\)  

P Value

Migraine

 Frequency

22.57 (5.49)

12.75 (10.75)

0.018

 Intensity

7.43 (1.24)

5.95 (1.88)

0.053

Cognitive measures

 ROCF-c / TFT-c

32.61 (3.1)

33.25 (2.09)

0.888

 ROCF-m / TFT-m

18.46 (4.01)

21.38 (7.78)

0.075

 TMT-A

45.89 (20.89)

49.33 (46.04)

0.068

 TMT-B

92.97 (44.85)

104.25 (99.18)

0.530

Emotional state

 HADS—A

5.64 (2.53)

5.75 (3.28)

0.730

 HADS—D

3.5 (1.7)

3.42 (2.78)

0.187

 BDI-II

5.64 (1.6)

5.42 (4.93)

0.422

Quality of life

 SF-36 PF

80 (14.14)

87.5 (12.52)

0.190

 SF-36 RP

35.71 (38.87)

54.17 (41.06)

0.194

 SF-36 BP

35.36 (18.93)

44.92 (15.2)

0.195

 SF-36 GH

55.36 (12.16)

58.33 (14.97)

0.279

 SF-36 VT

48.04 (17.02)

53.54 (17.44)

0.196

 SF-36 SF

74.11 (24.25)

83.33 (17.94)

0.427

 SF- 36 RE

59.55 (47.47)

77.75 (35.81)

0.465

 SF-36 MH

66 (19.3)

75.58 (12.28)

0.060

 PSQI-GS

7.08 (3.68)

6.5 (3.97)

0.403

  1. ROCF-c Rey-Osterrieth Complex Figure test, copy task, ROCF-m Rey-Osterrieth Complex Figure test, memory task, TFT-c Taylor Figure test, copy task, TFT-m Taylor Figure test, memory task, TMT-A Trail Making Test A, attention test, TMT-B Trail Making Test B, divided attention test, HADS-A Hospital Anxiety and Depression Scale, anxiety subscale, HADS-D Hospital Anxiety and Depression Scale, depression subscale, BDI-II Beck Depression Inventory II, SF-36 PF 36-item Short Form Health Survey, physical functioning, SF-36 RP role-physical, SF-36 BP bodily pain, SF-36 GH general health, SF-36 VT vitality, SF-36 SF social functioning, SF-36 RE role-emotional, SF-36 MH mental health, PSQI-GS Pittsburgh Sleep Quality Index, global score