Characteristics | Patients, No. (%) | Standardized Difference | |
---|---|---|---|
Migraine cohort (n = 44,195) | Matched controls (n = 44,195) | ||
Sex | |||
Male | 14,967 (33.9) | 14,967 (33.9) | 0 |
Female | 29,228 (66.1) | 29,228 (66.1) | |
Age, mean, (SD), y | 55.3 (9.4) | 55.3 (9.4) | 0 |
Household income level | |||
Medical aid program | 369 (0.8) | 369 (0.8) | 0 |
First | 3,942 (8.9) | 3,942 (8.9) | |
Second | 3,361 (7.6) | 3,361 (7.6) | |
Third | 3,461 (7.8) | 3,461 (7.8) | |
Fourth | 3,454 (7.8) | 3,454 (7.8) | |
Fifth | 3,509 (7.9) | 3,509 (7.9) | |
Sixth | 3,732 (8.4) | 3,732 (8.4) | |
Seventh | 4,352 (9.8) | 4,352 (9.8) | |
Eighth | 4,960 (11.2) | 4,960 (11.2) | |
Ninth | 6,255 (14.2) | 6,255 (14.2) | |
Tenth | 6,800 (15.4) | 6,800 (15.4) | |
Residential area | |||
Urban | 17,510 (39.6) | 17,629 (39.9) | 0.006 |
Rural | 26,685 (60.4) | 26,566 (60.1) | |
Registered disability | |||
No | 44,037 (99.6) | 43,932 (99.4) | 0.035 |
Yes | 158 (0.4) | 263 (0.6) | |
History of stroke | |||
No | 43,040 (97.4) | 43,024 (97.4) | 0.002 |
Yes | 1,155 (2.6) | 1,171 (2.6) | |
History of ischemic heart disease | |||
No | 43,683 (98.8) | 43,563 (98.6) | 0.024 |
Yes | 512 (1.2) | 632 (1.4) | |
History of diabetes mellitus | |||
No | 42,852 (97) | 42,566 (96.3) | 0.036 |
Yes | 1,343 (3) | 1,629 (3.7) | |
History of hypertension | |||
No | 41,923 (94.9) | 41,805 (94.6) | 0.012 |
Yes | 2,272 (5.1) | 2,390 (5.4) | |
History of antidepressant use (> 90 days) | |||
No | 36,189 (81.9) | 35,772 (80.9) | 0.024 |
Yes | 8,006 (18.1) | 8,423 (19.1) | |
Smoking status | |||
Never-smoker | 30,989 (70.1) | 30,675 (69.4) | 0.019 |
Ex-smoker | 5,327 (12.1) | 5,400 (12.2) | |
Current-smoker | 6,895 (15.6) | 7,036 (15.9) | |
Unspecified | 984 (2.2) | 1,084 (2.5) | |
BMI, kg/m2 | |||
< 25 | 29,397 (66.5) | 29,069 (65.8) | 0.021 |
≥ 25 | 14,768 (33.4) | 15,076 (34.1) | |
Unspecified | 30 (0.1) | 50 (0.1) | |
Drinking, units/weeks | |||
None | 29,937 (67.7) | 29,706 (67.2) | 0.013 |
≤ 7 | 7,147 (16.2) | 7,276 (16.5) | |
8–14 | 2,856 (6.5) | 2,847 (6.4) | |
> 15 | 3,317 (7.5) | 3,393 (7.7) | |
Unspecified | 938 (2.1) | 973 (2.2) |