Table 4 Top 15 pathways containing the list of KEGG results from the Mirpath v3 webtool analysis
Interictal vs healthy | Ictal vs interictal | ||||||
|---|---|---|---|---|---|---|---|
KEGG pathway | p-value | Number of genes | Number of miRNAs | KEGG pathway | p-value | Number of genes | Number of miRNAs |
ECM-receptor interaction | 6.11E-10 | 47 | 20 | Proteoglycans in cancer | 4.7E-07 | 122 | 18 |
Proteoglycans in cancer | 2.60E-08 | 114 | 23 | Prion diseases | 5.1E-05 | 16 | 11 |
PI3K-Akt signalling pathway | 3.14E-07 | 193 | 24 | Axon guidance | 5.1E-05 | 83 | 18 |
Morphine addiction | 3.14E-07 | 53 | 24 | Hippo signalling pathway | 8.86E-05 | 90 | 19 |
TGF-beta signalling pathway | 1.88E-06 | 49 | 18 | Biosynthesis of unsaturated fatty acids | 1.69E-04 | 12 | 8 |
Axon guidance | 1.88E-06 | 78 | 24 | Adrenergic signalling in cardiomyocytes | 2.52E-04 | 82 | 18 |
Transcriptional misregulation in cancer | 2.61E-06 | 101 | 23 | ErbB signalling pathway | 4.00E-04 | 56 | 17 |
GABAergic synapse | 3.09E-06 | 49 | 22 | TGF-beta signalling pathway | 9.09E-04 | 49 | 15 |
ErbB signalling pathway | 3.42E-06 | 55 | 21 | Fatty acid metabolism | 9.29E-04 | 27 | 11 |
Mucin type O- Glycan biosynthesis | 1.01E-05 | 18 | 13 | Phosphatidylinositol signalling system | 9.29E-04 | 51 | 17 |
FoxO signalling pathway | 1.01E-05 | 79 | 21 | Glutamatergic synapse | 9.29E-04 | 66 | 18 |
Glioma | 5.87E-05 | 40 | 18 | Wnt signalling pathway | 9.29E-04 | 81 | 19 |
Lysine degradation | 5.94E-05 | 29 | 21 | Pathways in cancer | 9.29E-04 | 218 | 23 |
Focal adhesion | 8.27E-05 | 118 | 23 | Mucin type O-Glycan biosynthesis | 9.53E-04 | 17 | 10 |
Signalling pathways regulating pluripotency of stem cells | 9.09E-05 | 83 | 23 | FoxO signalling pathway | 1.17E-03 | 80 | 17 |