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Fig. 3 | The Journal of Headache and Pain

Fig. 3

From: Avoid or seek light – a randomized crossover fMRI study investigating opposing treatment strategies for photophobia in migraine

Fig. 3

Functional activation induced by flickering light in patients and controls at baseline, and after Flash and Dark intervention, contrasted to the baseline (FWE 0.05 corr., cluster threshold = 10). At baseline, patients display higher activation in the primary visual cortex than controls. When contrasting Flash vs. baseline, patients show higher activation in the bilateral anterior insula compared to controls, while no difference was found for the contrast Dark vs. baseline

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