Fig. 2

Simplified distribution of acute medication optimization (mTOQ-4) at baseline and week 4. The mTOQ-4 was derived from the mTOQ-6 by selecting the items that best assessed efficacy: “2-h pain free,” “24-h relief,” “able to plan,” and “in control.” Each item is rated never (1), rarely (2), less than half the time (3), or half the time or more (4). Poorly optimized comprises the “very poor” and “poor” categories; optimized comprises “moderate” and “maximal.” Simplified subgroups consist of patients with mTOQ-4 total scores in very poor (0) and poor (1–5) categories together, along with patients with total scores in the moderate (6–7) and maximal (8) categories grouped together. mTOQ-4/mTOQ-6, 4-item/6-item Migraine Treatment Optimization Questionnaire