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Table 1 Demographics and characteristics of patients with cluster headache, according to pre-attack and pre-episode symptoms

From: Pre-attack and pre-episode symptoms in cluster headache: a multicenter cross-sectional study of 327 Chinese patients

  Total (N = 327) pre-attack symptoms p-
value
pre-episode symptoms p-
value
None (n = 58) Yes(n = 269) None(n = 259) Yes(n = 68)
Age 33.0 (28.0–39.0) 31.0 (27.0–38.0) 33.0 (28.0–39.0) 0.210 32.0 (28.0–38.0) 34.0 (28.0–39.0) 0.141
Gender     0.734    0.091
  Male 269 (82.3%) 47 (81.0%) 222 (82.5%)   218 (84.2%) 51 (75.0%)  
  Female 58 (17.7%) 11 (19.0%) 47 (17.5%)   41 (15.8%) 17 (25.0%)  
Smoking history 144 (44.0%) 18 (31.0%) 126 (46.8%) 0.037* 110 (42.5%) 34 (50.0%) 0.324
Drinking history 109 (33.3%) 13 (22.4%) 96 (35.7%) 0.064 85 (32.8%) 24 (35.3%) 0.774
Diagnosis     0.722    0.915
  eCH 318 (97.2%) 56 (96.6%) 262 (97.4%)   252 (97.3%) 66 (97.1%)  
  cCH 9 (2.8%) 2 (3.4%) 7 (2.6%)   7 (2.7%) 2 (2.9%)  
Duration (years) 10.0 (5.0–15.0) 8.0 (2.8–15.0) 10.0 (5.0–15.0) 0.328 10.0 (5.0–15.0) 10.0 (7.0–15.0) 0.026*
Family history of CH 19 (5.8%) 2 (3.4%) 17 (6.3%) 0.414 15 (5.8%) 4 (5.9%) 0.996
Coexisting other types 47 (14.4%) 6 (10.3%) 41 (15.2%) 0.185 35 (13.5%) 12 (17.6%) 0.234
Number of headache locations 3.0 (2.0–4.0) 2.0 (1.0–3.0) 3.0 (2.0–4.0) 0.009* 3.0 (2.0–4.0) 3.0 (2.0–4.0) 0.362
VAS 9.0 (8.0–10.0) 8.5 (7.5–10.0) 9.0 (8.0–10.0) 0.025* 9.0 (8.0–10.0) 9.5 (8.5–10.0) 0.046*
Duration of episode     0.089    0.364
Less than 2 weeks 34 (10.4%) 12 (20.7%) 22 (8.2%)   30 (11.6%) 4 (5.9%)  
From 2 weeks to less than 1 month 77 (23.5%) 14 (24.1%) 63 (23.4%)   57 (22.0%) 20 (29.4%)  
From 1 to 2 months 164 (50.2%) 24 (41.4%) 140 (52.1%)   127 (49.0%) 37 (54.4%)  
More than 2 months 43 (13.1%) 5 (8.6%) 38 (14.1%)   37 (14.3%) 6 (8.8%)  
First experience of cluster 9 (2.8%) 3 (5.2%) 6 (2.2%)   8 (3.1%) 1 (1.5%)  
Frequency of episode     0.996    0.092
Less than 1 time/year 136 (41.6%) 24 (41.4%) 112 (41.6%)   108 (41.7%) 28 (41.2%)  
1 time/year 121 (37.0%) 22 (37.9%) 99 (36.8%)   101 (39.0%) 20 (29.4%)  
More than 1 time/year 70 (21.4%) 12 (20.7%) 58 (21.6%)   50 (19.3%) 20 (29.4%)  
  1. *p<0.05;Data are presented as medians (interquartile ranges) or numbers (percentages)