Table 2 Univariate analyses & multiple logistic regression comparing baseline characteristics between responders and non-responders
Univariate Analyses | Multiple logistic regression | |||||
|---|---|---|---|---|---|---|
Variable | Responders (n = 68) | Non-responders (n = 30) | Difference (95% CI) | p-value | Odds ratio (95% CI) | p-value |
Age (mean ± SEM) | 44.8 ± 1.56 | 44.1 ± 2.16 | -0.62 (-6.07 – 4.84) | p = 0.8230* | 1.00 (0.96 to 1.04) | p = 0.8742 |
Gender (n [%] female) | 57 [83.8%] | 26 [86.7%] | OR 0.79 (0.26 – 2.66) | p > 0.9999† | 1.07 (0.29 to 4.55) | p = 0.9240 |
Baseline headache days (median [IQR]) | 27 [22–28] | 28 [28–28] | 1 (0 – 2) | p = 0.0006‡ | 1.03 (0.77 to 1.36) | p = 0.8058 |
Number of previously tried treatments (median [IQR]) | 7 [6.25–8] | 7 [6-8] | 0 (-1 – 0) | p = 0.3922‡ | 1.29 (0.90 to 1.87) | p = 0.1701 |
Any medication overuse at baseline (n [%])** | 35/63 [55.6%] | 13/28 [46.4%] | OR 1.44 (0.56 – 3.40) | p = 0.50† | 1.41 (0.52 – 3.89) | p = 0.5048 |
Daily headache at baseline (n [%]) | 33 [48.5%] | 26 [86.7%] | OR 0.15 (0.05 – 0.44) | p = 0.0003† | 0.11 (0.01 – 0.73) | p = 0.0395 |