Table 5 Multi-state model for the migraine preventive treatment: risk of discontinuation and analyzed covariates

Age^a

5.06

 < 0.001

 < 0.001

5.10

 < 0.001

 < 0.001

5.09

0.01

0.237

Gender

0.98

0.03

0.526

0.87

0.19

0.455

1.09

0.55

0.882

CCI

1.01

0.01

0.516

0.95

0.09

0.582

1.01

0.28

0.96

Time since diagnosis

0.99

0.01

0.048

0.97

0.04

0.432

1.04

0.11

0.730

Discontinuation (vs. 1st line)

n/a

0.24

0.35

 < 0.001

0.21

0.98

0.110