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Table 4 Levels of tryptophan metabolites in sera (mean ± SD)

From: Repeated inflammatory dural stimulation-induced cephalic allodynia causes alteration of gut microbial composition in rats

 

IS group

VEH group

p-value

L-TRP (µg/mL)

8.89 ± 1.45

9.09 ± 2.13

0.85

5-HT (µg/mL)

2.01 ± 0.32

1.79 ± 0.19

0.19

NAS (ng/mL)

1.05 ± 0.42

0.89 ± 0.58

0.59

5-HIAA (ng/mL)

16.8 ± 5.21

13.2 ± 7.59

0.36

L-KYN (µg/mL)

0.50 ± 0.15

0.49 ± 0.14

0.96

KYNA (ng/mL)

9.86 ± 11.1

15.3 ± 14.8

1.00

XA (ng/mL)

26.1 ± 4.64

29.0 ± 12.6

0.62

IAA (µg/mL)

0.10 ± 0.03

0.11 ± 0.04

0.58

IAld (ng/mL)

1.08 ± 0.70

1.28 ± 0.57

0.39

IEt (ng/mL)

1.18 ± 1.67

1.10 ± 0.95

0.45

ILA (ng/mL)

29.5 ± 5.12

31.9 ± 7.71

0.54

IA (ng/mL)

30.6 ± 19.4

38.5 ± 13.9

0.44

IPA (µg/mL)

0.42 ± 0.26

0.82 ± 0.56

0.15

  1. Levels of PiA, IAM and TRM could not be detected in sera