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Table 3 Levels of tryptophan metabolite in feces (mean ± SD)

From: Repeated inflammatory dural stimulation-induced cephalic allodynia causes alteration of gut microbial composition in rats

  IS group VEH group p-value
L-TRP (µg/g) 5.83 ± 2.36 7.77 ± 3.27 0.27
5-HT (µg/g) 1.10 ± 0.79 0.62 ± 0.33 0.21
NAS (µg/g) 0.13 ± 0.13 0.10 ± 0.03 0.55
5-HIAA (µg/g) 0.32 ± 0.20 0.32 ± 0.14 0.99
L-KYN (ng/g) 34.1 ± 12.5 40.3 ± 19.5 0.53
KYNA (µg/g) 0.50 ± 0.71 0.24 ± 0.21 0.09
XA (µg/g) 0.06 ± 0.03 0.15 ± 0.10 0.09
PiA (µg/g) 3.82 ± 2.72 4.36 ± 3.21 0.76
IAM (ng/g) 32.5 ± 8.83 12.8 ± 2.07 0.02*
IAA (µg/g) 0.81 ± 0.48 1.19 ± 0.98 0.42
IAld (µg/g) 0.29 ± 0.12 0.38 ± 0.16 0.33
TRM (µg/g) 0.81 ± 0.43 1.16 ± 0.38 0.17
IEt (µg/g) 0.12 ± 0.05 0.06 ± 0.03 0.03*
ILA (ng/g) 24.2 ± 17.8 39.5 ± 53.2 0.70
IA (ng/g) 32.4 ± 15.1 29.9 ± 8.63 0.73
IPA (µg/g) 0.54 ± 0.37 0.60 ± 0.28 0.75
  1. L-TRP L-tryptophan, 5-HT serotonin, NAS N-acetylserotonin, 5-HIAA 5-hydroxyindoleacetic acid, L-KYN L-kynurenine, KYNA kynurenic acid, XA xanthurenic acid, PiA picolinic acid, IAM indole-3-acetamide, IAA β-indole-3-acetic acid, IAld indole-3-aldehyde, TRM tryptamine, IEt tryptophol (indoleethanol), ILA indole-3-lactic acid, IA indole-3-β-acrylic acid, IPA indole-3-propionic acid