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Table 1 Baseline demographic and clinical parameters

From: Galcanezumab effect on “whole pain burden” and multidimensional outcomes in migraine patients with previous unsuccessful treatments: a real-world experience

Characteristics

N = 43

Age, mean ± SD

46 ± 13

Gender, n (%)

 Male

5 (11.63%)

 Female

38 (88.37%)

 Age at migraine onset (years), mean ± SD

18.83 ± 10.38

 Disease duration (years) mean ± SD

25.76 ± 15.35

 Concurrent oral preventive treatments, n (%)

12 (27.91%)

 Monotherapy

7 (16.28%)

 Polytherapy

5 (11.63%)

 Headache days/month, mean ± SD

20.56 ± 7.55

 Migraine attacks/month, mean ± SD

18.33 ± 7.15

 Chronic migraine pts. n (%)

35 (81.40%)

 Preventive classes failure, mean ± SD

3.7 ± 0.85

 Pain intensity (NRS), mean ± SD

8.95 ± 1.00

 Attack duration (hours), mean ± SD

9.03 ± 11.09

 Whole pain burden, median ± IQR

400 ± 1953

 Pain free 2 hours after painkiller intake, n (%)

25 (58.14%)

 Days with painkiller intake, mean ± SD

18.40 ± 8.37

 Painkiller intake/month, mean ± SD

22.58 ± 12.33

 MOH, n (%)

32 (91.43% of chronic migraine patients)

 HIT-6, median ± IQR

69 ± 9

 MIDAS, median ± IQR

90 ± 65

 MSQ, median ± IQR

75.71 ± 28.57

 BDI-II, median ± IQR

13.5 ± 15

 HDRS, median ± IQR

15 ± 10

 HARS, median ± IQR

13 ± 9

 Sleep problem INDEX II, median ± IQR

30.56 ± 22.22

 ASC-12, median ± IQR

6 ± 7

 PCS, median ± IQR

36.5 ± 14

  1. Values are mean ± standard deviation (SD) or ± interquartile range (IQR) or number (%)
  2. n number, pts. patients, NRS numerical rating scale, HIT-6 headache impact test-6, MIDAS migraine disability assessment scale, MOH medication overuse headache, MSQ migraine-specific quality-of-life questionnaire, BDI II Beck Depression Inventory, HDRS Hamilton Depression Rating Scale, HARS Hamilton Anxiety Rating Scale, ASC-12 Allodynia Symptom Checklist-12, PCS Pain Catastrophizing Scale