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Table 1 Baseline patient characteristics

From: A real-world study of acute and preventive medication use, adherence, and persistence in patients prescribed fremanezumab in the United States

  

Defined dose

 
 

Overall

(N = 987)

Quarterly

(n = 186)

Monthly

(n = 801)

P valuea (quarterly vs monthly)

Age, years, mean (SD)

46.8 (12.8)

47.1 (13.6)

46.7 (12.6)

0.697

Age, years, n (%)

 18–40

314 (31.8)

59 (31.7)

255 (31.8)

0.976

 41–64

595 (60.3)

104 (55.9)

491 (61.3)

0.176

  ≥ 65

78 (7.9)

23 (12.4)

55 (6.9)

0.012

Sex, n (%)

 Female

842 (85.3)

161 (86.6)

681 (85.0)

0.593

 Male

145 (14.7)

25 (13.4)

120 (15.0)

0.593

Migraine diagnosis, n (%)

 EM

594 (60.2)

123 (66.1)

471 (58.8)

 

 CM

393 (39.8)

63 (33.9)

330 (41.2)

 

Time from diagnosis to initial treatment, months, mean (SD)

29.2 (20.8)

27.1 (21.1)

29.6 (20.8)

0.141

Provider specialty, n (%)

 Neurology

526 (53.3)

82 (44.0)

444 (55.4)

0.005

 Family medicine

122 (12.4)

30 (16.1)

92 (11.5)

0.083

 Psychiatry

93 (9.4)

32 (17.2)

61 (7.6)

 < 0.001

 Specialist/nurse/PA

24 (2.4)

5 (2.7)

19 (2.4)

0.801

 Physical medicine

19 (1.9)

0

19 (2.4)

N/A

 Anesthesiology/pain management

13 (1.3)

8 (4.3)

5 (0.6)

 < 0.001

 Headache orofacial pain

15 (1.5)

0

15 (1.9)

N/A

 Otherb

175 (17.7)

29 (15.6)

146 (18.2)

0.396

Quan-Charlson comorbidity index score, mean (SD)

0.30 (0.84)

0.32 (0.99)

0.29 (0.80)

0.684

 0, n (%)

813 (82.4)

154 (82.8)

659 (82.3)

0.688

 1–3

161 (16.3)

28 (15.1)

133 (16.6)

0.764

 4–6

10 (1.0)

3 (1.6)

7 (0.9)

0.240

  > 6

3 (0.3)

1 (0.5)

2 (0.2)

0.113

Common (> 10%) migraine-specific comorbidities, n (%)

 Anxiety (including GAD)

152 (15.4)

30 (16.1)

122 (15.2)

0.760

 Depression (including MDD)

143 (14.5)

32 (17.2)

111 (13.9)

0.243

 High cholesterol

118 (12.0)

23 (12.4)

95 (11.9)

0.848

 Back pain

117 (11.9)

20 (10.8)

97 (12.1)

0.606

 Hypertension

115 (11.7)

24 (12.9)

91 (11.4)

0.555

 Neck pain

102 (10.3)

25 (13.4)

77 (9.6)

0.122

 Insomnia

100 (10.1)

26 (14.0)

74 (9.2)

0.054

  1. SD standard deviation, CM chronic migraine, EM episodic migraine, GAD generalized anxiety disorder, MDD major depressive disorder
  2. aP values calculated via chi-square test for dichotomous variables or Fisher’s exact test for continuous variables
  3. bOther includes specialist, allergy/immunology, other, or missing