Fig. 7

In elevated plus maze test, a) duration spent in open and b) closed arms (p = 0.99 and p = 0.99, respectively) and c) the number of open and d) closed arm entries were similar between hesperidin and DMSO groups (p = 0.88 and p = 0.6, respectively). e) Duration spent in open arms was lower (p = 0.003) and f) duration spent in closed arms was higher (p = 0.003) and g) number of open arm entries were lower (p = 0.006) and h) number of closed arm entries were similar (p = 0.12) in the elevated plus maze test in the chronic mefenamic acid group compared to its vehicle. i) Duration spent in open and j) closed arms and k) the number of open and l) closed arm entries were comparable between chronic mefenamic acid plus hesperidin and chronic mefenamic acid plus DMSO groups (p = 0.23, p = 0.32, p = 0.84, p = 0.37 respectively). *p < 0.05 vs. controls