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Table 2 Features of participants to the different studies: all included subjects, all vaccine recipients, placebo recipients, and single vaccine recipients

From: Headache onset after vaccination against SARS-CoV-2: a systematic literature review and meta-analysis

 

N. of studies

N. of participants

Median female percentage;

25th-75th percentile

(N. of studies)

Median age; 25th-75th percentile

(N. of studies)

Median percentage of subjects with chronic conditions;

25th-75th percentile

(N. of studies)

Median headache rank position among side effects;

25th-75th percentile

(N. of studies)

All included subjects

84

1,568,199

58.4%;

49.4–69.5%

(N = 76)

39.8;

35.5–49.9

(N = 62)

37.2%;

18.2–92.5%

(N = 19)

3rd;

3rd-4th

(N = 57)

All Vaccines recipients

84

1,522,830

59.4%;

49.1–71.1%

(N = 72)

41.0;

35.3–48.6

(N = 56)

34.7%;

16.9–96.3%

(N = 22)

3rd;

3rd-4th

(N = 56)

BNT162b2

41

1,047,545

64.3%;

52.3–71.7%

(N = 34)

43.5;

38.2–57.3

(N = 26)

85.0%;

39.4–100%

(N = 9)

3rd;

3rd-4th

(N = 32)

ChAdOx1

19

388,147

71.2%;

61.1–76.3%

(N = 12)

37.5;

35.8–49.7

(N = 8)

45.8%;

41.5–50.1%

(N = 2)

4th;

3rd-4th

(N = 12)

PiCoVacc

9

15,177

62.4%;

49.0%-67.7%

(N = 6)

35.8;

35.4–36.1

(N = 5)

15.8%;

15.2–16.3%

(N = 2)

3rd;

2nd-3rd

(N = 7)

mRNA-1273

5

16,575

51.8%;

41.1–64.4%

(N = 4)

64.7;

48.9–66.7

(N = 3)

100%;

n.a

(N = 1)

3rd;

2nd-3rd

(N = 3)

NVX-CoV2373

3

7,612

48.8%;

48.7–49.0%

(N = 2)

56.0;

n.a

(N = 1)

n.r

3rd;

2nd-3rd

(N = 2)

Placebo Recipients

21

45,760

52.4%;

47.6–54.2%

(N = 20)

43.3;

37.6–48.1

(N = 19)

13.8%;

4.8–26.9%

(N = 5)

3rd;

2nd-4th

(N = 18)

  1. Vaccines reported by less than three studies were not included in the table
  2. N.R. not reported, N.A. not available