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Fig. 13 | The Journal of Headache and Pain

Fig. 13

From: Lasmiditan and 5-Hydroxytryptamine in the rat trigeminal system; expression, release and interactions with 5-HT1 receptors

Fig. 13

Simplified overview of immunoreactivity within the rat trigeminal ganglion. The schematic is based on observations made in this, and previous studies [11, 39, 62]. A Expression of 5-HT, CGRP, neurokinin and PACAP-38 signalling elements in trigeminal neurons and glial cells. B Hypothetic CGRP and neurokinin receptor signalling within the nodes of Ranvier of trigeminal Aδ-fibres. Abbreviations; neurokinin A (NKA), neurokinin receptor 1 (NK1-R), neurokinin receptor 2 (NK2-R), peripheral nervous system (PNS), transient receptor potential ankyrin subtype 1 (TRPA1)

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The Journal of Headache and Pain

ISSN: 1129-2377

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